| ID Source | ID |
|---|---|
| PubMed CID | 1223727 |
| CHEMBL ID | 1462960 |
| CHEBI ID | 117074 |
| Synonym |
|---|
| HMS2573C13 |
| 1-[(4-bromophenyl)acetyl]-4-(2-pyridinyl)piperazine |
| smr000272469 |
| MLS000680741 |
| OPREA1_037153 |
| 2-(4-bromophenyl)-1-[4-(pyridin-2-yl)piperazin-1-yl]ethanone |
| STK423765 |
| CHEBI:117074 |
| AKOS001285467 |
| 2-(4-bromophenyl)-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone |
| CHEMBL1462960 |
| cambridge id 7306693 |
| Q27203700 |
| 2-(4-bromophenyl)-1-[4-(2-pyridinyl)-1-piperazinyl]ethanone |
| Z26736012 |
| Class | Description |
|---|---|
| piperazines | |
| pyridines | Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 28.1838 | 0.1778 | 14.3909 | 39.8107 | AID2147 |
| ClpP | Bacillus subtilis | Potency | 22.3872 | 1.9953 | 22.6730 | 39.8107 | AID651965 |
| TDP1 protein | Homo sapiens (human) | Potency | 20.5962 | 0.0008 | 11.3822 | 44.6684 | AID686979 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 79.4328 | 0.5318 | 15.4358 | 37.6858 | AID504845 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 39.8107 | 0.0060 | 26.1688 | 89.1251 | AID540317 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 29.9349 | 0.1683 | 16.4040 | 67.0158 | AID720504 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 1.7783 | 1.9953 | 25.5327 | 50.1187 | AID624287 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| polyadenylate-binding protein 1 | Homo sapiens (human) | IC50 (µMol) | 66.0000 | 4.9100 | 23.7029 | 76.1900 | AID602259; AID602260 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| negative regulation of inflammatory response to antigenic stimulus | Guanine nucleotide-binding protein G | Homo sapiens (human) |
| renal water homeostasis | Guanine nucleotide-binding protein G | Homo sapiens (human) |
| G protein-coupled receptor signaling pathway | Guanine nucleotide-binding protein G | Homo sapiens (human) |
| regulation of insulin secretion | Guanine nucleotide-binding protein G | Homo sapiens (human) |
| cellular response to glucagon stimulus | Guanine nucleotide-binding protein G | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| G protein activity | Guanine nucleotide-binding protein G | Homo sapiens (human) |
| adenylate cyclase activator activity | Guanine nucleotide-binding protein G | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| plasma membrane | Guanine nucleotide-binding protein G | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | |||
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6 | A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | |||
| AID1159537 | qHTS screening for TAG (triacylglycerol) accumulators in algae | 2017 | Plant physiology, Aug, Volume: 174, Issue:4 | Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
|---|---|---|---|---|---|---|
| levoplast | [no description available] | medium | 1 | 0 | C-nitro compound | |
| hippuric acid | [no description available] | medium | 1 | 0 | N-acylglycine | human blood serum metabolite; uremic toxin |
| xanthine | [no description available] | medium | 1 | 0 | xanthine | Saccharomyces cerevisiae metabolite |
| atrolactic acid | [no description available] | medium | 1 | 0 | 2-hydroxy monocarboxylic acid | |
| etofylline | [no description available] | medium | 1 | 0 | oxopurine | |
| n-acetyltryptophan | [no description available] | medium | 1 | 0 | N-acetyl-amino acid; tryptophan derivative | metabolite |
| ethacridine | [no description available] | medium | 1 | 0 | acridines | |
| altretamine | [no description available] | medium | 1 | 0 | triamino-1,3,5-triazine | |
| 2,5-di-tert-butylhydroquinone | [no description available] | medium | 1 | 0 | hydroquinones | |
| cx546 | [no description available] | medium | 1 | 0 | ||
| diphenhydramine | [no description available] | medium | 1 | 0 | ether; tertiary amino compound | anti-allergic agent; antidyskinesia agent; antiemetic; antiparkinson drug; antipruritic drug; antitussive; H1-receptor antagonist; local anaesthetic; muscarinic antagonist; oneirogen; sedative |
| diuron | [no description available] | medium | 1 | 0 | 3-(3,4-substituted-phenyl)-1,1-dimethylurea; dichlorobenzene | environmental contaminant; mitochondrial respiratory-chain inhibitor; photosystem-II inhibitor; urea herbicide; xenobiotic |
| ibuprofen | [no description available] | medium | 1 | 0 | monocarboxylic acid | antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; environmental contaminant; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug; radical scavenger; xenobiotic |
| ipriflavone | [no description available] | medium | 1 | 0 | aromatic ether; isoflavones | bone density conservation agent |
| mebendazole | [no description available] | medium | 1 | 0 | aromatic ketone; benzimidazoles; carbamate ester | antinematodal drug; microtubule-destabilising agent; tubulin modulator |
| nocodazole | [no description available] | medium | 1 | 0 | aromatic ketone; benzimidazoles; carbamate ester; thiophenes | antimitotic; antineoplastic agent; microtubule-destabilising agent; tubulin modulator |
| piribedil | [no description available] | medium | 1 | 0 | N-arylpiperazine | |
| procainamide | [no description available] | medium | 1 | 0 | benzamides | anti-arrhythmia drug; platelet aggregation inhibitor; sodium channel blocker |
| prometone | [no description available] | medium | 1 | 0 | diamino-1,3,5-triazine; methoxy-1,3,5-triazine | environmental contaminant; herbicide; xenobiotic |
| propanil | [no description available] | medium | 1 | 0 | anilide; dichlorobenzene | herbicide |
| sulfadimethoxine | [no description available] | medium | 1 | 0 | aromatic ether; pyrimidines; substituted aniline; sulfonamide antibiotic; sulfonamide | antiinfective agent; antimicrobial agent; drug allergen; environmental contaminant; xenobiotic |
| sulfamethazine | [no description available] | medium | 1 | 0 | pyrimidines; sulfonamide antibiotic; sulfonamide | antibacterial drug; antiinfective agent; antimicrobial agent; carcinogenic agent; drug allergen; EC 2.5.1.15 (dihydropteroate synthase) inhibitor; environmental contaminant; ligand; xenobiotic |
| sulfathiazole | [no description available] | medium | 1 | 0 | 1,3-thiazoles; substituted aniline; sulfonamide antibiotic; sulfonamide | antiinfective agent; drug allergen; EC 2.5.1.15 (dihydropteroate synthase) inhibitor; environmental contaminant; xenobiotic |
| testosterone | [no description available] | medium | 1 | 0 | 3-hydroxy steroid | androgen |
| 2-hydroxybenzylbenzimidazole | [no description available] | medium | 1 | 0 | ||
| etimizol | [no description available] | medium | 1 | 0 | ||
| nifenalol | [no description available] | medium | 1 | 0 | C-nitro compound | |
| bis(4-hydroxyphenyl)sulfone | [no description available] | medium | 1 | 0 | bisphenol; sulfone | endocrine disruptor; metabolite |
| 8-hydroxyquinoline-5-sulfonic acid | [no description available] | medium | 1 | 0 | ||
| salicylanilide | [no description available] | medium | 1 | 0 | benzanilide fungicide; salicylamides; salicylanilides | |
| 2-phenylbutyric acid | [no description available] | medium | 1 | 0 | benzenes; monocarboxylic acid | human xenobiotic metabolite |
| 4,4'-dimethoxybenzophenone | [no description available] | medium | 1 | 0 | ||
| 6-phenyl-1,3,5-triazine-2,4-diamine | [no description available] | medium | 1 | 0 | ||
| quinaldic acid | [no description available] | medium | 1 | 0 | quinolinemonocarboxylic acid | human metabolite; Saccharomyces cerevisiae metabolite |
| N-(2-methoxyphenyl)acetamide | [no description available] | medium | 1 | 0 | acetamides; methoxybenzenes | |
| fast red b | [no description available] | medium | 1 | 0 | ||
| methylenebis(chloroaniline) | [no description available] | medium | 1 | 0 | chloroaniline | metabolite |
| di-(4-aminophenyl)ether | [no description available] | medium | 1 | 0 | aromatic ether | |
| diphenylguanidine | [no description available] | medium | 1 | 0 | guanidines | allergen |
| 4-Anilino-4-oxobutanoic acid | [no description available] | medium | 1 | 0 | anilide | |
| mephobarbital | [no description available] | medium | 1 | 0 | barbiturates | anticonvulsant |
| etryptamine | [no description available] | medium | 1 | 0 | indoles | |
| sulfacetamide | [no description available] | medium | 1 | 0 | ||
| cinchophen | [no description available] | medium | 1 | 0 | quinolines | |
| 2-aminobenzothiazole | [no description available] | medium | 1 | 0 | benzothiazoles | |
| carzenide | [no description available] | medium | 1 | 0 | sulfonamide | |
| nitrilotriacetic acid | [no description available] | medium | 1 | 0 | NTA; tricarboxylic acid | carcinogenic agent; nephrotoxic agent |
| n-(2-cyanoethyl)-2-phenylethylamine | [no description available] | medium | 1 | 0 | ||
| cyclooctane | [no description available] | medium | 1 | 0 | ||
| triphenyltetrazolium chloride | [no description available] | medium | 1 | 0 | organic chloride salt | dye; indicator |
| 2,7-diacetylaminofluorene | [no description available] | medium | 1 | 0 | ||
| 3,4-pyridinedicarboxylic acid | [no description available] | medium | 1 | 0 | pyridinedicarboxylic acid | |
| 4-(benzoylamino)-2-hydroxybenzoic acid | [no description available] | medium | 1 | 0 | benzamides | |
| tropic acid | [no description available] | medium | 1 | 0 | 3-hydroxy monocarboxylic acid | human xenobiotic metabolite |
| 8-hydroxy-7-iodo-5-quinolinesulfonic acid | [no description available] | medium | 1 | 0 | hydroxyquinoline | |
| 1-acetylisatin | [no description available] | medium | 1 | 0 | indoledione | |
| 4-cumylphenol | [no description available] | medium | 1 | 0 | diarylmethane | |
| 5-methylisatin | [no description available] | medium | 1 | 0 | ||
| 2-hydrazinobenzothiazole | [no description available] | medium | 1 | 0 | ||
| 1,2,3-trimethoxybenzene | [no description available] | medium | 1 | 0 | methoxybenzenes | plant metabolite |
| 2-amino-5-chlorobenzophenone | [no description available] | medium | 1 | 0 | ||
| diphenamid | [no description available] | medium | 1 | 0 | diarylmethane | |
| 4-(4-nitrobenzyl)pyridine | [no description available] | medium | 1 | 0 | ||
| 5-methyl-3-phenylisoxazole-4-carboxylic acid | [no description available] | medium | 1 | 0 | ||
| 2-acetylbenzofuran | [no description available] | medium | 1 | 0 | ||
| pyrazon | [no description available] | medium | 1 | 0 | benzenes; organochlorine compound; primary amino compound; pyridazinone | environmental contaminant; herbicide; xenobiotic |
| 2-amino-5-nitrobenzophenone | [no description available] | medium | 1 | 0 | ||
| (4-tert-Butyl-phenoxy)-acetic acid | [no description available] | medium | 1 | 0 | monocarboxylic acid | |
| lenacil | [no description available] | medium | 1 | 0 | cyclopentapyrimidine | agrochemical; environmental contaminant; herbicide; xenobiotic |
| chlordesmethyldiazepam | [no description available] | medium | 1 | 0 | benzodiazepine | |
| 2-amino-2',5-dichlorobenzophenone | [no description available] | medium | 1 | 0 | ||
| 2-(2'-hydroxyphenyl)benzimidazole | [no description available] | medium | 1 | 0 | ||
| 4-phthalimidobutyric acid | [no description available] | medium | 1 | 0 | ||
| azabutyrone | [no description available] | medium | 1 | 0 | ||
| 2-(2-hydroxyphenyl)benzothiazole | [no description available] | medium | 1 | 0 | benzothiazoles; phenols | geroprotector |
| 4,5-dichlorocatechol | [no description available] | medium | 1 | 0 | ||
| n-butylbenzenesulfonamide | [no description available] | medium | 1 | 0 | sulfonamide | neurotoxin; plant metabolite |
| 3-phenoxybenzoic acid | [no description available] | medium | 1 | 0 | phenoxybenzoic acid | human xenobiotic metabolite; marine xenobiotic metabolite |
| 2-(2-hydroxyethylmercapto)benzothiazole | [no description available] | medium | 1 | 0 | ||
| carboxin | [no description available] | medium | 1 | 0 | anilide fungicide; anilide; enamide; organosulfur heterocyclic compound; oxacycle; secondary carboxamide | antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor |
| meturin | [no description available] | medium | 1 | 0 | ||
| 2-bromo-N-phenylbenzamide | [no description available] | medium | 1 | 0 | benzamides | |
| 4-chlorohippuric acid | [no description available] | medium | 1 | 0 | ||
| 4-chlorophenoxyacetic acid | [no description available] | medium | 1 | 0 | chlorophenoxyacetic acid; monochlorobenzenes | phenoxy herbicide |
| 2,5-dichloro-1,4-phenylenediamine | [no description available] | medium | 1 | 0 | ||
| metribuzin | [no description available] | medium | 1 | 0 | 1,2,4-triazines; cyclic ketone; organic sulfide | agrochemical; environmental contaminant; herbicide; xenobiotic |
| 2,5-dimethyl-3-furancarboxanilide | [no description available] | medium | 1 | 0 | ||
| moricizine hydrochloride | [no description available] | medium | 1 | 0 | hydrochloride | anti-arrhythmia drug |
| 2-benzimidazolylguanidine | [no description available] | medium | 1 | 0 | aminoimidazole | |
| diflubenzuron | [no description available] | medium | 1 | 0 | benzoylurea insecticide; monochlorobenzenes | insect sterilant |
| pentafluorobenzoyl-n-phenylethylamine | [no description available] | medium | 1 | 0 | ||
| thidiazuron | [no description available] | medium | 1 | 0 | ureas | |
| phenthiazamine | [no description available] | medium | 1 | 0 | ||
| 5,5-diphenylbarbituric acid | [no description available] | medium | 1 | 0 | ||
| 3-acetamidobenzoic acid | [no description available] | medium | 1 | 0 | ||
| dazoxiben hydrochloride | [no description available] | medium | 1 | 0 | ||
| succinylsulfanilamide | [no description available] | medium | 1 | 0 | ||
| benzylaminopurine | [no description available] | medium | 1 | 0 | 6-aminopurines | cytokinin; plant metabolite |
| ciprofloxacin hydrochloride anhydrous | [no description available] | medium | 1 | 0 | hydrochloride | antibacterial drug; antiinfective agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; topoisomerase IV inhibitor |
| src-820 r | [no description available] | medium | 1 | 0 | ||
| n(4)-acetylsulfadiazine | [no description available] | medium | 1 | 0 | acetamides; pyrimidines; sulfonamide | marine xenobiotic metabolite |
| 4-nitro-alpha-acetylamino-beta-hydroxypropiophenone | [no description available] | medium | 1 | 0 | ||
| formetamide | [no description available] | medium | 1 | 0 | ||
| isbufylline | [no description available] | medium | 1 | 0 | ||
| phenylacetylglycine | [no description available] | medium | 1 | 0 | monocarboxylic acid amide; monocarboxylic acid; N-acylglycine | human metabolite; mouse metabolite |
| N-benzoylanthranilic acid | [no description available] | medium | 1 | 0 | amidobenzoic acid | |
| butinoline | [no description available] | medium | 1 | 0 | diarylmethane | |
| n-(2-carboxyphenyl)glycine | [no description available] | medium | 1 | 0 | ||
| n,n-dimethyl-4-anisidine | [no description available] | medium | 1 | 0 | ||
| n-benzoylpiperidine | [no description available] | medium | 1 | 0 | benzamides; N-acylpiperidine | |
| 2-phenylcyclopropanecarboxylic acid | [no description available] | medium | 1 | 0 | ||
| n-demethylantipyrine | [no description available] | medium | 1 | 0 | pyrazoles; ring assembly | |
| 3-(2-pyridyl)-5,6-diphenyl-1,2,4-triazine | [no description available] | medium | 1 | 0 | 1,2,4-triazines | |
| 2-amino-5-bromopyridine | [no description available] | medium | 1 | 0 | ||
| n-benzoylalanine, (dl-ala)-isomer | [no description available] | medium | 1 | 0 | alanine derivative; N-acyl-amino acid | metabolite |
| bicinchoninic acid | [no description available] | medium | 1 | 0 | ||
| betamipron | [no description available] | medium | 1 | 0 | organonitrogen compound; organooxygen compound | |
| benzoylpropionic acid | [no description available] | medium | 1 | 0 | 4-oxo monocarboxylic acid | hapten |
| Evoxine | [no description available] | medium | 1 | 0 | organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle | |
| 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid | [no description available] | medium | 1 | 0 | harmala alkaloid | |
| N-Benzylphthalimide | [no description available] | medium | 1 | 0 | isoindoles | |
| pyromellitic diimide | [no description available] | medium | 1 | 0 | ||
| 4'-bromosalicylanilide | [no description available] | medium | 1 | 0 | ||
| 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane | [no description available] | medium | 1 | 0 | bisphenol | |
| terephthalamide | [no description available] | medium | 1 | 0 | benzenedicarboxamide | |
| 3(2h)-pyridazinone, 4-chloro-5-(dimethylamino)-2-phenyl- | [no description available] | medium | 1 | 0 | ||
| 2-nitrophenylacetic acid | [no description available] | medium | 1 | 0 | C-nitro compound; phenylacetic acids | |
| onychine | [no description available] | medium | 1 | 0 | ||
| 4'-methoxyflavone | [no description available] | medium | 1 | 0 | ether; flavonoids | |
| 1,3-diphenyl-2-aminopropane | [no description available] | medium | 1 | 0 | ||
| 2,2-diphenylpropionic acid | [no description available] | medium | 1 | 0 | ||
| 3,4-dimethoxyphenylacetamide | [no description available] | medium | 1 | 0 | ||
| 2-amino-5-bromobenzoic acid | [no description available] | medium | 1 | 0 | ||
| 2-(1H-benzimidazol-2-yl)aniline | [no description available] | medium | 1 | 0 | benzimidazoles; primary arylamine; substituted aniline | geroprotector |
| N-Acetylhomoveratrylamine | [no description available] | medium | 1 | 0 | acetamides | |
| 2-chlorobenzenesulfonamide | [no description available] | medium | 1 | 0 | ||
| 4-nitrophenyl dimethylcarbamate | [no description available] | medium | 1 | 0 | ||
| 8-(4-tolylsulfonylamino)quinoline | [no description available] | medium | 1 | 0 | sulfonamide | |
| 5-methoxyindole-3-carbaldehyde | [no description available] | medium | 1 | 0 | indoles | |
| 2-oxo-1,2-dihydroquinoline-4-carboxylic acid | [no description available] | medium | 1 | 0 | quinolinemonocarboxylic acid | |
| 6-methoxy-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one | [no description available] | medium | 1 | 0 | beta-carbolines | |
| pd 147953 | [no description available] | medium | 1 | 0 | ||
| fenozan | [no description available] | medium | 1 | 0 | ||
| 5-phenylbarbituric acid | [no description available] | medium | 1 | 0 | ||
| diethylpropion hydrochloride | [no description available] | medium | 1 | 0 | hydrochloride | appetite depressant |
| 1-(4'-nitrophenyl)-2-aminopropane-1,3-diol | [no description available] | medium | 1 | 0 | ||
| beta-hydroxyphenylalanine | [no description available] | medium | 1 | 0 | ||
| 3-(n-salicyloyl)amino-1,2,4-triazole | [no description available] | medium | 1 | 0 | ||
| 7-chloro-4-aminoquinoline | [no description available] | medium | 1 | 0 | aminoquinoline | |
| acridine-9-carboxylic acid | [no description available] | medium | 1 | 0 | ||
| 1-phenazinecarboxylic acid | [no description available] | medium | 1 | 0 | aromatic carboxylic acid; monocarboxylic acid; phenazines | antifungal agent; antimicrobial agent; bacterial metabolite |
| 4,5-diphenyl-1,5-dihydroimidazol-2-one | [no description available] | medium | 1 | 0 | stilbenoid | |
| 2-hydroxy-1,2-bis(methoxyphenyl)ethanone | [no description available] | medium | 1 | 0 | ||
| 4-methyl-N-(phenylmethyl)benzenesulfonamide | [no description available] | medium | 1 | 0 | sulfonamide | |
| 4-n-butylaminobenzoic acid | [no description available] | medium | 1 | 0 | aromatic amino acid | |
| fluoren-9-ol | [no description available] | medium | 1 | 0 | ||
| 1-(2-carboxyethyl)uracil | [no description available] | medium | 1 | 0 | ||
| 1-benzylindole | [no description available] | medium | 1 | 0 | ||
| 2,3-bis(2-pyridinyl)quinoxaline | [no description available] | medium | 1 | 0 | quinoxaline derivative | |
| 3,3',5,5'-tetrachlorobiphenyl-4,4'-diol | [no description available] | medium | 1 | 0 | dichlorobenzene; hydroxybiphenyls | |
| 5-nitro-2-(1-piperidinyl)pyridine | [no description available] | medium | 1 | 0 | C-nitro compound | |
| 2-amino-5,7-dimethyl-1,8-naphthyridine | [no description available] | medium | 1 | 0 | ||
| 5-benzyloxytryptophan | [no description available] | medium | 1 | 0 | ||
| 2,5-diethoxy-4-morpholinoaniline | [no description available] | medium | 1 | 0 | ||
| 3-hydroxy-3-phenacyloxindole | [no description available] | medium | 1 | 0 | ||
| carbobenzoxyphenylalanine, (dl-phe)-isomer | [no description available] | medium | 1 | 0 | ||
| gamma-fagarine | [no description available] | medium | 1 | 0 | organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle | |
| 3-carboxymethyl-6-benzyl-2,5-diketopiperazine | [no description available] | medium | 1 | 0 | organonitrogen compound; organooxygen compound | |
| 4-fluorobenzenesulfonamide | [no description available] | medium | 1 | 0 | ||
| emoxypine succinate | [no description available] | medium | 1 | 0 | ||
| n-carbamyltryptophan | [no description available] | medium | 1 | 0 | ||
| 2,4,6-trimethoxyacetophenone | [no description available] | medium | 1 | 0 | ||
| 1-(2-hydroxyethyl)-3,5-diphenyl-1h-pyrazole | [no description available] | medium | 1 | 0 | ||
| 4-methyoxybenzoyl-n-glycine | [no description available] | medium | 1 | 0 | N-acylglycine | |
| 5-ethoxy-2-ethylmercaptobenzimidazole | [no description available] | medium | 1 | 0 | ||
| 5(6)-1(2h)-phthalazinonyl-4(1h)-benzimidazole-2-carbamate methyl ester | [no description available] | medium | 1 | 0 | ||
| n-phenyliminodiacetic acid | [no description available] | medium | 1 | 0 | ||
| teomorfolin | [no description available] | medium | 1 | 0 | ||
| 1-(1,3-benzodioxol-5-yl)-3-(1-piperidinyl)-1-propanone | [no description available] | medium | 1 | 0 | benzodioxoles | |
| n-(aminocarbonyl)-2-chlorobenzenesulfonamide | [no description available] | medium | 1 | 0 | ||
| 3-hydroxy-2-quinoxalinepropionic acid | [no description available] | medium | 1 | 0 | ||
| 8-(methylsulfonylamino)quinoline | [no description available] | medium | 1 | 0 | ||
| n(4)-acetylsulfamonomethoxine | [no description available] | medium | 1 | 0 | ||
| 8-(4-benzenesulfonylamino)quinoline | [no description available] | medium | 1 | 0 | ||
| methindione | [no description available] | medium | 1 | 0 | ||
| 3,4-dihydroxybenzophenone | [no description available] | medium | 1 | 0 | ||
| gamma-propanol | [no description available] | medium | 1 | 0 | ||
| 2-[(3-oxo-1-cyclohexenyl)amino]benzonitrile | [no description available] | medium | 1 | 0 | benzenes; nitrile | |
| isonicotinylamide gaba | [no description available] | medium | 1 | 0 | ||
| 5-fluorotryptamine monohydrochloride | [no description available] | medium | 1 | 0 | ||
| 4-iodo-n-(2-(4-morpholinyl)ethyl)benzamide | [no description available] | medium | 1 | 0 | ||
| 3-(hydroxyacetyl)indole | [no description available] | medium | 1 | 0 | indoles | |
| n-(4-aminophenylsulfonyl)morpholine | [no description available] | medium | 1 | 0 | ||
| 1H-indol-3-yl-(4-methoxyphenyl)methanone | [no description available] | medium | 1 | 0 | N-acylindole | |
| 2-amino-5-phenyl-1,3,4-thiadiazole | [no description available] | medium | 1 | 0 | ||
| N-(1-phenylethyl)acetamide | [no description available] | medium | 1 | 0 | acetamides; secondary carboxamide | |
| alpha-(trichloromethyl)-4-pyridineethanol | [no description available] | medium | 1 | 0 | pyridines | |
| ml 204 | [no description available] | medium | 1 | 0 | ||
| eudesmin | [no description available] | medium | 1 | 0 | ||
| 2-amino-4-methyl-3-nitropyridine | [no description available] | medium | 1 | 0 | ||
| 4,4-bis(hydroxymethyl)-2-phenyl-2-oxazoline | [no description available] | medium | 1 | 0 | ||
| n-acetylhistidine | [no description available] | medium | 1 | 0 | histidine derivative; N-acetyl-amino acid | |
| 1-(1-oxo-2-phenylethyl)-4-piperidinecarboxylic acid | [no description available] | medium | 1 | 0 | acetamides | |
| 1-(4-chlorophenyl)-3-(2-ethoxyphenyl)urea | [no description available] | medium | 1 | 0 | ureas | |
| 4-methoxyxanthone | [no description available] | medium | 1 | 0 | ||
| N-(4-nitrophenyl)-2-phenoxyacetamide | [no description available] | medium | 1 | 0 | C-nitro compound | |
| 1-phenylindolin-2-one | [no description available] | medium | 1 | 0 | ||
| 1-(benzenesulfonyl)indole | [no description available] | medium | 1 | 0 | sulfonamide | |
| 2,4,4,6-Tetramethyl-1,4-dihydro-3,5-pyridinedicarbonitrile | [no description available] | medium | 1 | 0 | dihydropyridine | |
| pifithrin mu | [no description available] | medium | 1 | 0 | benzenes | |
| 2-benzyloxybenzaldehyde | [no description available] | medium | 1 | 0 | ||
| 2-guanidine-4-methylquinazoline | [no description available] | medium | 1 | 0 | ||
| N-phenylcarbamic acid 2-phenoxyethyl ester | [no description available] | medium | 1 | 0 | carbamate ester | |
| 3,4-dihydro-2H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-3-ol | [no description available] | medium | 1 | 0 | benzimidazoles | |
| mequindox | [no description available] | medium | 1 | 0 | ||
| N-[2-(dimethylamino)ethyl]-2,2-diphenylacetamide | [no description available] | medium | 1 | 0 | diarylmethane | |
| Girgensonine | [no description available] | medium | 1 | 0 | nitrile | |
| Dubinidine | [no description available] | medium | 1 | 0 | organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle | |
| N-[4-(methanesulfonamido)phenyl]acetamide | [no description available] | medium | 1 | 0 | sulfonamide | |
| 4-(2-oxazolo[4,5-b]pyridinyl)aniline | [no description available] | medium | 1 | 0 | 1,3-oxazoles | |
| 2-[(4-nitrophenyl)methylthio]-1,3-benzoxazole | [no description available] | medium | 1 | 0 | benzoxazole | |
| 3-oxido-4,5-dihydro-[1,2,5]oxadiazolo[3,4-f]cinnolin-3-ium | [no description available] | medium | 1 | 0 | pyridazines | |
| 3-(2,4-difluoroanilino)-5,5-dimethyl-1-cyclohex-2-enone | [no description available] | medium | 1 | 0 | substituted aniline | |
| 1-phenyl-4-pyrazolol | [no description available] | medium | 1 | 0 | pyrazoles; ring assembly | |
| 3-(3,5-dimethyl-1-pyrazolyl)-1,2-benzothiazole 1,1-dioxide | [no description available] | medium | 1 | 0 | benzothiazoles | |
| 3-benzamido-2-benzofurancarboxamide | [no description available] | medium | 1 | 0 | benzofurans | |
| N-[2-(4-methoxyphenyl)ethyl]acetamide | [no description available] | medium | 1 | 0 | acetamides | |
| N-[2-(3-methylphenoxy)ethyl]-1H-1,2,4-triazole-5-carboxamide | [no description available] | medium | 1 | 0 | aromatic ether | |
| 2-(1H-indol-3-ylthio)acetic acid | [no description available] | medium | 1 | 0 | indoles | |
| 3-bromo-N-[2-(4-nitroanilino)ethyl]benzamide | [no description available] | medium | 1 | 0 | carbonyl compound; organohalogen compound | |
| 3-Methylbenzofuran-2-carboxylic acid | [no description available] | medium | 1 | 0 | benzofurans | |
| 5-(3,4-dimethoxyphenyl)-2H-tetrazole | [no description available] | medium | 1 | 0 | tetrazoles | |
| 1-(4-fluorophenyl)sulfonyl-4-(2-methoxyphenyl)piperazine | [no description available] | medium | 1 | 0 | piperazines | |
| 4-[[bis(2-hydroxyethyl)amino]methyl]-2,6-ditert-butylphenol | [no description available] | medium | 1 | 0 | alkylbenzene | |
| 2-phenylindole-3-carbaldehyde | [no description available] | medium | 1 | 0 | ||
| 4-(2-pyridinylthio)benzofuro[3,2-d]pyrimidine | [no description available] | medium | 1 | 0 | aryl sulfide | |
| 5-(4-nitrophenyl)-4-phenyl-2-thiazolamine | [no description available] | medium | 1 | 0 | C-nitro compound | |
| 3-[6-(4-aminophenyl)-2-phenyl-4-pyrimidinyl]aniline | [no description available] | medium | 1 | 0 | pyrimidines | |
| 7-methoxyisoflavone | [no description available] | medium | 1 | 0 | 7-methoxyisoflavones | |
| LSM-32392 | [no description available] | medium | 1 | 0 | monoterpenoid | |
| N-[2-(1-cyclohexenyl)ethyl]-4-(4-morpholinylmethyl)benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| 1-(1-benzimidazolyl)-3-(1-cyclohex-3-enylmethoxy)-2-propanol | [no description available] | medium | 1 | 0 | benzimidazoles | |
| N-[2-(2-furanylmethylthio)ethyl]-4-methoxybenzenesulfonamide | [no description available] | medium | 1 | 0 | sulfonamide | |
| 3-acetamido-5-chloro-2-benzofurancarboxylic acid | [no description available] | medium | 1 | 0 | benzofurans | |
| [4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-(2,6-dimethoxyphenyl)methanone | [no description available] | medium | 1 | 0 | dimethoxybenzene | |
| 4-[4-methyl-6-(4-methyl-1-piperazinyl)-2-pyrimidinyl]morpholine | [no description available] | medium | 1 | 0 | N-arylpiperazine | |
| haplamine | [no description available] | medium | 1 | 0 | organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle | |
| 5-(3,4-dimethoxyphenyl)-1H-1,2,4-triazol-3-amine | [no description available] | medium | 1 | 0 | triazoles | |
| 2-ethoxy-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| 2-[(5-methyl-1H-1,2,4-triazol-3-yl)thio]-1-phenylethanone | [no description available] | medium | 1 | 0 | aromatic ketone | |
| 1-ethyl-6-methoxy-4-oxo-3-quinolinecarboxylic acid | [no description available] | medium | 1 | 0 | quinolines | |
| 2-(pyridin-4-yl)-4-(pyrrolidin-1-yl)quinazoline | [no description available] | medium | 1 | 0 | pyridines; pyrrolidines; quinazolines | |
| scp 1 | [no description available] | medium | 1 | 0 | ||
| N-(3-acetamidophenyl)-4-methoxybenzamide | [no description available] | medium | 1 | 0 | benzamides | |
| N-(3-acetamidophenyl)-3-chlorobenzamide | [no description available] | medium | 1 | 0 | benzamides | |
| 4-methoxy-N-(5-methyl-3-isoxazolyl)benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| N-(2-fluorophenyl)-4-phenylmethoxybenzamide | [no description available] | medium | 1 | 0 | benzamides | |
| N-[4-(diethylamino)phenyl]-2-furancarboxamide | [no description available] | medium | 1 | 0 | aromatic amide; furans | |
| N-(2-furanylmethyl)-2-benzofurancarboxamide | [no description available] | medium | 1 | 0 | benzofurans | |
| 5-(2-phenylethyl)-1,3,4-thiadiazol-2-amine | [no description available] | medium | 1 | 0 | aromatic amine; thiadiazoles | |
| te 5 | [no description available] | medium | 1 | 0 | ||
| 2-[[anilino(oxo)methyl]amino]-4,5-dimethyl-3-thiophenecarboxamide | [no description available] | medium | 1 | 0 | ureas | |
| N-(4,6-dimethyl-2-pyrimidinyl)-1,3-benzothiazol-2-amine | [no description available] | medium | 1 | 0 | benzothiazoles | |
| 6-methylflavone | [no description available] | medium | 1 | 0 | ||
| 2-methoxy-N-(2-pyridinyl)benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| 2-chloro-N-(2-phenylethyl)benzamide | [no description available] | medium | 1 | 0 | carbonyl compound; organohalogen compound | |
| N1-(4H-1,2,4-triazol-4-yl)-4-nitrobenzamide | [no description available] | medium | 1 | 0 | C-nitro compound | |
| N-[2-(1-cyclohexenyl)ethyl]-4-fluorobenzamide | [no description available] | medium | 1 | 0 | carbonyl compound; organohalogen compound | |
| tioxazafen | [no description available] | medium | 1 | 0 | 1,2,4-oxadiazole; thiophenes | agrochemical; nematicide |
| N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-2-thiophen-2-ylacetamide | [no description available] | medium | 1 | 0 | aromatic amide | |
| 1-(4-Methoxyphenyl)-2-nitroethylene | [no description available] | medium | 1 | 0 | methoxybenzenes | |
| brd32048 | [no description available] | medium | 1 | 0 | methoxybenzenes; substituted aniline | |
| 2-(4-chloro-3-methylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamide | [no description available] | medium | 1 | 0 | aromatic ether | |
| 2-(3,4-dichlorophenyl)imidazo[1,2-a]pyrimidine | [no description available] | medium | 1 | 0 | imidazoles | |
| 5-(2-phenyl-4-triazolyl)-2H-tetrazole | [no description available] | medium | 1 | 0 | triazoles | |
| N-cyclohexyl-2,3-dihydroindole-1-carboxamide | [no description available] | medium | 1 | 0 | indolyl carboxylic acid | |
| 4-(benzylsulfanyl)thieno[2,3-d]pyrimidine | [no description available] | medium | 1 | 0 | aryl sulfide; benzenes; thienopyrimidine | |
| 2-methyl-5-(5-methyl-2-furanyl)-3-(1-pyrrolyl)-4-thieno[2,3-d]pyrimidinone | [no description available] | medium | 1 | 0 | organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound | |
| 1-[2-(dimethylamino)ethyl]-5-methoxy-N-methyl-2-indolecarboxamide | [no description available] | medium | 1 | 0 | indolecarboxamide | |
| N-(5-ethyl-1,3,4-thiadiazol-2-yl)-3-methoxybenzamide | [no description available] | medium | 1 | 0 | benzamides | |
| 4-(1H-benzimidazol-2-yl)quinoline | [no description available] | medium | 1 | 0 | quinolines | |
| 1-(4-Chlorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)thio]ethan-1-one | [no description available] | medium | 1 | 0 | aromatic ketone | |
| N-(2,5-dimethylphenyl)-2-benzofurancarboxamide | [no description available] | medium | 1 | 0 | aromatic amide; furans | |
| N-(4-methoxyphenyl)-2-benzofurancarboxamide | [no description available] | medium | 1 | 0 | aromatic amide; furans | |
| 2-(9h-xanthen-9-yl)-malonic acid | [no description available] | medium | 1 | 0 | xanthenes | |
| 1-(1,3-benzothiazol-2-yl)-3-phenylurea | [no description available] | medium | 1 | 0 | ureas | |
| 1-hydroxy-2-phenyl-1,5,6,7-tetrahydro-4H-benzimidazol-4-one | [no description available] | medium | 1 | 0 | imidazoles | |
| N-(4-acetamidophenyl)-2-bromobenzamide | [no description available] | medium | 1 | 0 | benzamides | |
| 4-bromo-N-phenacylbenzamide | [no description available] | medium | 1 | 0 | aromatic ketone | |
| 1-(2,3-dihydroindol-1-yl)-2-(phenylthio)ethanone | [no description available] | medium | 1 | 0 | indoles | |
| N-[6-methyl-2-(4-methylphenyl)-5-benzotriazolyl]-3-pyridinecarboxamide | [no description available] | medium | 1 | 0 | triazoles | |
| N,N-dimethyl-N'-p-tolylsulfamide | [no description available] | medium | 1 | 0 | sulfamides | marine xenobiotic metabolite |
| 2-(1-piperidinylmethyl)phenol | [no description available] | medium | 1 | 0 | ||
| 2,6-bis(benzimidazol-2-yl)pyridine | [no description available] | medium | 1 | 0 | benzimidazoles | |
| 1-cyclohexyl-3-(2-phenylethyl)urea | [no description available] | medium | 1 | 0 | benzenes | |
| 1-(3,5-dichlorophenyl)-3-phenylurea | [no description available] | medium | 1 | 0 | ureas | |
| 1-(cyclohexylmethyl)-4-phenylpiperazine | [no description available] | medium | 1 | 0 | piperazines | |
| N-phenethyl-2-furamide | [no description available] | medium | 1 | 0 | aromatic amide; heteroarene | |
| paromomycin sulfate | [no description available] | medium | 1 | 0 | ||
| N,N,2-trimethyl-1-phenyl-5-benzimidazolesulfonamide | [no description available] | medium | 1 | 0 | benzimidazoles | |
| N-(phenylmethyl)-4-(3-pyridinyl)-2-thiazolamine | [no description available] | medium | 1 | 0 | aralkylamine | |
| N-(4-hydroxy-2-methyl-5-propan-2-ylphenyl)benzenesulfonamide | [no description available] | medium | 1 | 0 | monoterpenoid | |
| 2-amino-5-ethyl-4-(2-furanyl)-6-propyl-3-pyridinecarbonitrile | [no description available] | medium | 1 | 0 | nitrile; pyridines | |
| 2-ethoxy-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| vu0099704 | [no description available] | medium | 1 | 0 | ||
| 3-(4-chlorophenyl)-2,5-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one | [no description available] | medium | 1 | 0 | pyrazoles; ring assembly | |
| 1-(2-chloro-6-fluorophenyl)-[1,2,4]triazolo[4,3-a]quinoline | [no description available] | medium | 1 | 0 | triazoles | |
| 2-methyl-N-(1-methyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl)propanamide | [no description available] | medium | 1 | 0 | pyrroloquinoline | |
| 2-methyl-5-[(2-methyl-4-quinolinyl)thio]-1,3,4-thiadiazole | [no description available] | medium | 1 | 0 | aryl sulfide | |
| 5-methyl-1-(4-nitrophenyl)-2-oxo-2,5-dihydro-1h-pyrido(3,2-b)indole-3-carbonitrile | [no description available] | medium | 1 | 0 | ||
| (3-hydroxy-5,6,7,8-tetrahydro-4H-cyclohepta[d]imidazol-2-yl)-phenylmethanone | [no description available] | medium | 1 | 0 | aromatic ketone | |
| 2-fluoro-N-phenacylbenzamide | [no description available] | medium | 1 | 0 | aromatic ketone | |
| 4-(methoxymethyl)-6-methyl-2-(2-methylanilino)-3-pyridinecarbonitrile | [no description available] | medium | 1 | 0 | nitrile; pyridines | |
| 1-azepanyl-[2-methoxy-4-(methylthio)phenyl]methanone | [no description available] | medium | 1 | 0 | carbonyl compound; thiol | |
| GS4012 free base | [no description available] | medium | 1 | 0 | aryl sulfide; monomethoxybenzene; pyridines | VEGF activator |
| N-[1-(4-methylphenyl)-5-benzimidazolyl]acetamide | [no description available] | medium | 1 | 0 | benzimidazoles | |
| 2-(4-methylanilino)-1-(4-nitrophenyl)ethanone | [no description available] | medium | 1 | 0 | aromatic ketone | |
| N-(2,6-dimethylphenyl)-N(2)-(3,5-dimethylphenyl)glycinamide | [no description available] | medium | 1 | 0 | amino acid amide; glycine derivative | |
| 2-[4-[(3-fluorophenyl)methyl]-1-piperazinyl]pyrimidine | [no description available] | medium | 1 | 0 | N-arylpiperazine | |
| 1-[(3,4-dimethoxyphenyl)methyl]-4-(2,3-dimethylphenyl)piperazine | [no description available] | medium | 1 | 0 | piperazines | |
| 4-Piperidinobenzoic acid | [no description available] | medium | 1 | 0 | piperidines | |
| 1-(2-methoxyphenyl)-4-(3-thiophenylmethyl)piperazine | [no description available] | medium | 1 | 0 | piperazines | |
| N-(1-methyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl)-2-(1-pyrrolidinyl)acetamide | [no description available] | medium | 1 | 0 | pyrroloquinoline | |
| 4-[(1H-benzimidazol-2-ylthio)methyl]-2-thiazolamine | [no description available] | medium | 1 | 0 | benzimidazoles | |
| 4-[(4-phenyl-2-thiazolyl)amino]benzenesulfonamide | [no description available] | medium | 1 | 0 | sulfonamide | |
| N-[7-(1-oxopropyl)-2,3-dihydro-1,4-benzodioxin-6-yl]benzamide | [no description available] | medium | 1 | 0 | benzodioxine | |
| N-[3-chloro-4-(1-pyrrolidinyl)phenyl]-2-furancarboxamide | [no description available] | medium | 1 | 0 | aromatic amide; furans | |
| n-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine | [no description available] | medium | 1 | 0 | ||
| 8-(3,5-dimethyl-1-pyrazolyl)quinoline | [no description available] | medium | 1 | 0 | quinolines | |
| 2'-nitroflavone | [no description available] | medium | 1 | 0 | ||
| N-(4-methoxyphenyl)-3,4-dihydroquinolin-2-amine | [no description available] | medium | 1 | 0 | aminoquinoline | |
| 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one | [no description available] | medium | 1 | 0 | aromatic compound | |
| vrt 532 | [no description available] | medium | 1 | 0 | ||
| 4-[[4-(2,5-dimethylphenyl)-1-piperazinyl]methyl]-2-methoxyphenol | [no description available] | medium | 1 | 0 | piperazines | |
| 1-piperonylpiperidine | [no description available] | medium | 1 | 0 | ||
| 2-[(3-fluorophenyl)methyl-(phenylmethyl)amino]ethanol | [no description available] | medium | 1 | 0 | aromatic amine | |
| 2-methoxy-4-[[2-(methylthio)anilino]methyl]phenol | [no description available] | medium | 1 | 0 | aromatic amine | |
| 6-ethyl-5-methyl-2-thiophen-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one | [no description available] | medium | 1 | 0 | pyrazolopyrimidine | |
| N-[4-(2-methyl-4-thiazolyl)phenyl]benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| N-(6-phenyl-5-imidazo[2,1-b]thiazolyl)benzamide | [no description available] | medium | 1 | 0 | imidazoles | |
| 2-(phenylmethylthio)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole | [no description available] | medium | 1 | 0 | aryl sulfide | |
| 5-methyl-N-(4,5,6-trimethyl-2-pyrimidinyl)-1,3-benzoxazol-2-amine | [no description available] | medium | 1 | 0 | benzoxazole | |
| 1-(4-methoxyphenyl)-3-(6-methyl-2-pyridinyl)urea | [no description available] | medium | 1 | 0 | ureas | |
| 2-{[hydroxy(2-methoxyphenyl)methylidene]amino}acetic acid | [no description available] | medium | 1 | 0 | N-acylglycine | |
| (4-methoxyphenyl)-(3-methyl-2-propyl-4-imidazolyl)methanone | [no description available] | medium | 1 | 0 | aromatic ketone | |
| N-(3-acetamidophenyl)-2-chlorobenzamide | [no description available] | medium | 1 | 0 | benzamides | |
| N4,N4-dimethyl-N1-(4-nitro-1,1-dioxo-2,5-dihydrothiophen-3-yl)benzene-1,4-diamine | [no description available] | medium | 1 | 0 | dialkylarylamine; tertiary amino compound | |
| 2-bromo-N-(3-methoxyphenyl)benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| 2-methoxy-4-[(4-methyl-1,4-diazepan-1-yl)methyl]-6-nitrophenol | [no description available] | medium | 1 | 0 | aromatic ether; C-nitro compound | |
| 3-[[(2,5-dimethyl-3-furanyl)-oxomethyl]amino]benzoic acid | [no description available] | medium | 1 | 0 | aromatic amide; furans | |
| 1-(4-ethoxyphenyl)-3-(6-quinoxalinyl)urea | [no description available] | medium | 1 | 0 | quinoxaline derivative | |
| 2-(dimethylsulfamoylamino)-9H-fluorene | [no description available] | medium | 1 | 0 | fluorenes | |
| 4-chloro-1-ethyl-3-nitro-2-quinolinone | [no description available] | medium | 1 | 0 | nitro compound; quinolines | |
| 4-chloro-3-nitro-1-(phenylmethyl)-2-quinolinone | [no description available] | medium | 1 | 0 | quinolines | |
| 2,5-dimethyl-1-(phenylmethyl)pyrrole-3,4-dicarboxaldehyde | [no description available] | medium | 1 | 0 | arenecarbaldehyde | |
| 2-(2-chloro-6-fluorophenyl)-1-(2,4-dihydroxyphenyl)ethanone | [no description available] | medium | 1 | 0 | stilbenoid | |
| 4-methyl-N-(3-nitrophenyl)-5-phenyl-3-thiophenecarboxamide | [no description available] | medium | 1 | 0 | aromatic amide | |
| N-(5-amino-1-phenyl-1,2,4-triazol-3-yl)-2,2,2-trichloroacetamide | [no description available] | medium | 1 | 0 | triazoles | |
| N-(2-fluoro-5-methylphenyl)-3-phenylpropanamide | [no description available] | medium | 1 | 0 | anilide | |
| N-[(4-fluorophenyl)methyl]-2-thiophen-2-ylacetamide | [no description available] | medium | 1 | 0 | organofluorine compound | |
| 4-tert-butyl-N-(1,4-dioxo-2,3-dihydrophthalazin-5-yl)benzamide | [no description available] | medium | 1 | 0 | phthalazines | |
| N-[2-(2-methylpropyl)-1,3-dioxo-5-isoindolyl]-2-furancarboxamide | [no description available] | medium | 1 | 0 | phthalimides | |
| 6-(1,4,5,7-tetramethyl-6-pyrrolo[3,4-d]pyridazinyl)quinoline | [no description available] | medium | 1 | 0 | quinolines | |
| 2-(3,4-dimethoxyphenyl)-1-(2,4,6-trihydroxyphenyl)ethanone | [no description available] | medium | 1 | 0 | stilbenoid | |
| 5-(3-chloro-4-methylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole | [no description available] | medium | 1 | 0 | oxadiazole; ring assembly | |
| 5-(phenylmethyl)-3-(2-pyridinyl)-1,2,4-oxadiazole | [no description available] | medium | 1 | 0 | pyridines | |
| 2-methyl-5-(1-pyrrolidinyl)isoindole-1,3-dione | [no description available] | medium | 1 | 0 | phthalimides | |
| (2'-(4-aminophenyl)-(2,5'-bi-1h-benzimidazol)-5-amine) | [no description available] | medium | 1 | 0 | benzimidazoles | |
| N-(4-bromo-2-fluorophenyl)-2-methyl-3-furancarboxamide | [no description available] | medium | 1 | 0 | aromatic amide; furans | |
| 6,7,8,9-tetrahydro-5H-carbazole-3-carbohydrazide | [no description available] | medium | 1 | 0 | carbazoles | |
| N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-pyrazinecarboxamide | [no description available] | medium | 1 | 0 | primary carboxamide; pyrazines; secondary carboxamide | |
| N-(1,3-benzodioxol-5-yl)-5-methyl-2-furancarboxamide | [no description available] | medium | 1 | 0 | benzodioxoles | |
| 1-cyclohexyl-3-(2,3-dihydro-1,4-benzodioxin-6-yl)urea | [no description available] | medium | 1 | 0 | benzodioxine | |
| 8-[(2-methyl-5-nitro-1,2,4-triazol-3-yl)thio]quinoline | [no description available] | medium | 1 | 0 | aryl sulfide | |
| 1-[2-(2-chlorophenoxy)ethyl]benzimidazole | [no description available] | medium | 1 | 0 | benzimidazoles | |
| 4,5-dimethyl-2-[4-(3-nitrophenyl)-2-thiazolyl]-1H-pyrazol-3-one | [no description available] | medium | 1 | 0 | C-nitro compound | |
| 2-(4-fluoro-N-methylsulfonylanilino)-N-(3-methylphenyl)acetamide | [no description available] | medium | 1 | 0 | sulfonamide | |
| 1-(4-fluorophenyl)-2-(2-pyridinylthio)ethanone | [no description available] | medium | 1 | 0 | aromatic ketone | |
| 3-methyl-6-(1-pyrrolidinyl)-[1,2,4]triazolo[4,3-b]pyridazine | [no description available] | medium | 1 | 0 | triazolopyridazine | |
| N-(3-acetylphenyl)-2-thiophen-2-ylacetamide | [no description available] | medium | 1 | 0 | aromatic ketone | |
| oncrasin-1 | [no description available] | medium | 1 | 0 | arenecarbaldehyde; indoles; monochlorobenzenes | antineoplastic agent; apoptosis inducer |
| N-[2-(4-fluorophenyl)ethyl]-4-nitrobenzamide | [no description available] | medium | 1 | 0 | C-nitro compound | |
| 5-(1-methyl-2-benzimidazolyl)-2-thiophenecarboxaldehyde | [no description available] | medium | 1 | 0 | benzimidazoles | |
| N-(4-anilinophenyl)-2-methylpropanamide | [no description available] | medium | 1 | 0 | anilide | |
| N-(2-fluorophenyl)-3-phenylpropanamide | [no description available] | medium | 1 | 0 | anilide | |
| 1-[(Phenylthio)acetyl]piperidine | [no description available] | medium | 1 | 0 | N-acylpiperidine | |
| N-(3-hydroxyphenyl)-5-methyl-3-furancarboxamide | [no description available] | medium | 1 | 0 | aromatic amide; furans | |
| 3-(4-methoxyphenyl)-5-(4-methylphenyl)-1,2,4-oxadiazole | [no description available] | medium | 1 | 0 | oxadiazole; ring assembly | |
| 4-[(4-carboxy-2,6-dimethoxyphenoxy)methyl]-5-methyl-2-furancarboxylic acid | [no description available] | medium | 1 | 0 | trihydroxybenzoic acid | |
| 4-(4-morpholinylmethyl)-3-quinolinol | [no description available] | medium | 1 | 0 | quinolines | |
| 2-bromo-N-[3-(1-oxopropylamino)phenyl]benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| 3-acetyl-2-methylbenzo[f]benzofuran-4,9-dione | [no description available] | medium | 1 | 0 | naphthofuran | |
| 5-(4-chlorophenyl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-furancarboxamide | [no description available] | medium | 1 | 0 | aromatic amide; heteroarene | |
| 1-azepanyl-[4-[(phenylthio)methyl]phenyl]methanone | [no description available] | medium | 1 | 0 | benzamides | |
| 1-(5-ethyl-2,4-dihydroxyphenyl)-2-(2-fluorophenoxy)ethanone | [no description available] | medium | 1 | 0 | aromatic ketone | |
| N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(2-nitrophenyl)acetamide | [no description available] | medium | 1 | 0 | acetamides | |
| 3,4,5-triethoxy-N-(1H-1,2,4-triazol-5-yl)benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| 1-propylsulfonyl-4-(2-pyridinyl)piperazine | [no description available] | medium | 1 | 0 | piperazines; pyridines | |
| 2-(2-phenylethylthio)-3-pyridinecarboxylic acid | [no description available] | medium | 1 | 0 | aromatic carboxylic acid; pyridines | |
| 2-(2,3-dimethylphenoxy)-N-pyridin-4-ylacetamide | [no description available] | medium | 1 | 0 | aromatic ether | |
| 2-[[anilino(oxo)methyl]amino]-N-(phenylmethyl)benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| N-(5-acetyl-4-methyl-2-thiazolyl)-5-bromo-2-furancarboxamide | [no description available] | medium | 1 | 0 | thiazoles | |
| 1-cyclohexyl-3-(3-ethylphenyl)urea | [no description available] | medium | 1 | 0 | ureas | |
| n-phenylpiracetam | [no description available] | medium | 1 | 0 | ||
| 2-[(1-methyl-5-tetrazolyl)thio]-N-(2-phenylphenyl)acetamide | [no description available] | medium | 1 | 0 | biphenyls | |
| N-[3-chloro-4-(1-pyrrolidinyl)phenyl]-2-nitrobenzamide | [no description available] | medium | 1 | 0 | benzamides | |
| 4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(2,6-dimethylphenyl)benzamide | [no description available] | medium | 1 | 0 | isoquinolines | |
| 5-(4-bromophenyl)-N-(2-methoxyphenyl)-2-furancarboxamide | [no description available] | medium | 1 | 0 | aromatic amide; furans | |
| 3-[[(3,5-dichloro-4-ethoxyphenyl)-oxomethyl]amino]benzoic acid | [no description available] | medium | 1 | 0 | benzamides | |
| 1,4-bis(thiophen-2-ylsulfonyl)piperazine | [no description available] | medium | 1 | 0 | N-sulfonylpiperazine; thiophenes | |
| 2-bromo-N-[3-(1-oxobutylamino)phenyl]benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| 1-(2-fluorophenyl)-4-[(6-nitro-1,3-benzodioxol-5-yl)methyl]piperazine | [no description available] | medium | 1 | 0 | piperazines | |
| n-(1-benzyl-4-piperidinyl)-2,4-dichlorobenzamide | [no description available] | medium | 1 | 0 | ||
| 2-[[2-(5-methyl-2-thiophenyl)-2-oxoethyl]thio]-3-phenyl-4-quinazolinone | [no description available] | medium | 1 | 0 | quinazolines | |
| 1-(2,1,3-benzothiadiazol-5-yl)-3-[4-(4-morpholinyl)phenyl]urea | [no description available] | medium | 1 | 0 | morpholines | |
| ethyl 4-{N-[(4-chlorophenyl)sulfonyl]-N-methylglycyl}piperazine-1-carboxylate | [no description available] | medium | 1 | 0 | carbamate ester; sulfonamide | |
| LSM-4563 | [no description available] | medium | 1 | 0 | aromatic ketone | |
| 1-(4-chloro-3-methoxyphenyl)sulfonyl-4-phenylpiperazine | [no description available] | medium | 1 | 0 | piperazines | |
| N-[4-[(3,4-dimethoxyphenyl)sulfamoyl]phenyl]acetamide | [no description available] | medium | 1 | 0 | sulfonamide | |
| 4-chloro-3-(1-piperidinylsulfonyl)-N-(2-thiazolyl)benzamide | [no description available] | medium | 1 | 0 | sulfonamide | |
| 1-(2,5-dimethoxyphenyl)sulfonyl-4-(phenylmethyl)piperazine | [no description available] | medium | 1 | 0 | sulfonamide | |
| 2-(4-methoxyphenyl)-N-[4-[(5-methyl-3-isoxazolyl)sulfamoyl]phenyl]acetamide | [no description available] | medium | 1 | 0 | sulfonamide | |
| 4-[4-(benzenesulfonyl)-1-piperazinyl]-2-methylquinoline | [no description available] | medium | 1 | 0 | piperazines; pyridines | |
| 1-(6-methoxy-2,2,4-trimethyl-1-quinolinyl)-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thio]ethanone | [no description available] | medium | 1 | 0 | quinolines | |
| N2-phenyl-6-[[(1-phenyl-5-tetrazolyl)thio]methyl]-1,3,5-triazine-2,4-diamine | [no description available] | medium | 1 | 0 | tetrazoles | |
| 2-[(4,6-dimethyl-2-pyrimidinyl)thio]-N-(4,5-diphenyl-2-oxazolyl)acetamide | [no description available] | medium | 1 | 0 | 1,3-oxazoles | |
| 2-amino[1,3]thiazolo[4,5-d]pyrimidine-5,7-diol | [no description available] | medium | 1 | 0 | thiazolopyrimidine | |
| 3-[[(2-cyclohexyl-1,3-dioxo-5-isoindolyl)-oxomethyl]amino]benzoic acid | [no description available] | medium | 1 | 0 | aromatic amide | |
| 3-[[[3-(1-azepanylsulfonyl)-4-chlorophenyl]-oxomethyl]amino]benzoic acid | [no description available] | medium | 1 | 0 | benzamides | |
| 2-(4-bromophenyl)-N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)acetamide | [no description available] | medium | 1 | 0 | acetamides | |
| 5-(1,3-benzodioxol-5-ylsulfamoyl)-2-methoxybenzoic acid | [no description available] | medium | 1 | 0 | methoxybenzoic acid | |
| N-cycloheptyl-1-(4-methylphenyl)sulfonyl-4-piperidinecarboxamide | [no description available] | medium | 1 | 0 | sulfonamide | |
| 3-(2-chlorophenyl)-5-methyl-N-[4-[2-(4-morpholinyl)-2-oxoethoxy]phenyl]-4-isoxazolecarboxamide | [no description available] | medium | 1 | 0 | aromatic amide | |
| N-[3-[[(4-nitrophenyl)-oxomethyl]amino]phenyl]-2-furancarboxamide | [no description available] | medium | 1 | 0 | benzamides | |
| 3-methyl-1,5-dithiophen-2-ylpentane-1,5-dione | [no description available] | medium | 1 | 0 | aromatic ketone | |
| N-(2-methyl-1,3-benzothiazol-6-yl)-4-(4-morpholinylsulfonyl)benzamide | [no description available] | medium | 1 | 0 | sulfonamide | |
| 4-(dimethylsulfamoyl)-N-(4-thiophen-2-yl-2-thiazolyl)benzamide | [no description available] | medium | 1 | 0 | sulfonamide | |
| 3-chloro-N-[4-[(1-oxo-2-phenylethyl)amino]phenyl]benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| N-(3,4-dimethoxyphenyl)-4-[(4-phenyl-1-piperazinyl)methyl]benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| stk295900 | [no description available] | medium | 1 | 0 | ||
| 1-(3-chlorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine | [no description available] | medium | 1 | 0 | piperazines | |
| 2-[4-[[4-(4-methoxyphenyl)-1-phthalazinyl]amino]phenyl]acetamide | [no description available] | medium | 1 | 0 | pyridazines; ring assembly | |
| 1-(2-fluorophenyl)-3-[5-(2-fluorophenyl)-1,3,4-thiadiazol-2-yl]urea | [no description available] | medium | 1 | 0 | ureas | |
| N-[5-[(4-methoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-furancarboxamide | [no description available] | medium | 1 | 0 | methoxybenzenes | |
| N-(1,3-benzodioxol-5-yl)-4-methyl-1-phthalazinamine | [no description available] | medium | 1 | 0 | phthalazines | |
| SMER 28 | [no description available] | medium | 1 | 0 | organobromine compound; quinazolines; secondary amino compound | autophagy inducer |
| N-[4-(4-morpholinyl)phenyl]carbamic acid butyl ester | [no description available] | medium | 1 | 0 | morpholines | |
| 4-(4-chlorophenoxy)-1-(4-morpholinyl)-1-butanone | [no description available] | medium | 1 | 0 | aromatic ether | |
| 4-(4-chlorophenoxy)-1-(1-piperidinyl)-1-butanone | [no description available] | medium | 1 | 0 | N-acylpiperidine | |
| N-(3-phenylpropyl)methanesulfonamide | [no description available] | medium | 1 | 0 | benzenes | |
| 4-acetamido-N-(2-methoxyethyl)benzamide | [no description available] | medium | 1 | 0 | amidobenzoic acid | |
| 2-methyl-N-(2,3,4,5,6-pentafluorophenyl)-3-furancarboxamide | [no description available] | medium | 1 | 0 | aromatic amide; furans | |
| 3,4-dihydro-2H-quinolin-1-yl-(4-propoxyphenyl)methanone | [no description available] | medium | 1 | 0 | quinolines | |
| 5-bromo-N-(2-phenylphenyl)-2-furancarboxamide | [no description available] | medium | 1 | 0 | aromatic amide; furans | |
| 2-[2-(4-chlorophenoxy)ethylthio]pyrimidine | [no description available] | medium | 1 | 0 | aromatic ether | |
| 3-(3-bromoanilino)-1-(5-methyl-2-furanyl)-1-propanone | [no description available] | medium | 1 | 0 | aralkylamine | |
| 4-[2-(4-bromo-2-chlorophenoxy)-1-oxoethyl]-1-piperazinecarboxylic acid ethyl ester | [no description available] | medium | 1 | 0 | piperazinecarboxylic acid | |
| 2-[2-[[3-(1,3-benzoxazol-2-yl)anilino]-oxomethyl]phenyl]benzoic acid | [no description available] | medium | 1 | 0 | benzamides | |
| 1-[2-(2-chlorophenoxy)ethoxy]-2-methoxy-4-methylbenzene | [no description available] | medium | 1 | 0 | methoxybenzenes | |
| N-[4-[(4-sulfamoylphenyl)sulfamoyl]phenyl]cyclopropanecarboxamide | [no description available] | medium | 1 | 0 | sulfonamide | |
| 4-[2-[2-(4-bromo-2-chlorophenoxy)ethoxy]ethyl]morpholine | [no description available] | medium | 1 | 0 | aromatic ether | |
| N-[2-(2-phenylphenoxy)ethyl]-2-furancarboxamide | [no description available] | medium | 1 | 0 | biphenyls | |
| 5,6,7,8-tetrafluoro-2-(2,3,4,5,6-pentafluorophenyl)-4h-1-benzopyran-4-one | [no description available] | medium | 1 | 0 | ||
| 2-[bis(5-methyl-2-furanyl)methyl]-6-nitrophenol | [no description available] | medium | 1 | 0 | nitrophenol | |
| 2-(4-nitrophenyl)-N-(2-oxolanylmethyl)-4-quinazolinamine | [no description available] | medium | 1 | 0 | quinazolines | |
| 2-(4-hydroxy-1,3-thiazol-2-yl)-1-phenylethan-1-one | [no description available] | medium | 1 | 0 | aromatic ketone | |
| Methyl(2-furoylamino)acetic acid | [no description available] | medium | 1 | 0 | N-acyl-amino acid | |
| 5-nitro-8-(1-pyrrolidinyl)quinoline | [no description available] | medium | 1 | 0 | nitro compound; quinolines | |
| 2-(3-oxo-2,4-dihydro-1H-quinoxalin-2-yl)-N-phenylacetamide | [no description available] | medium | 1 | 0 | amino acid amide | |
| 2-[(4-methylphenyl)sulfonylamino]pentanoic acid | [no description available] | medium | 1 | 0 | sulfonamide | |
| 4,6-dimorpholino-n-(4-nitrophenyl)-1,3,5-triazin-2-amine | [no description available] | medium | 1 | 0 | ||
| 1-[(3-chlorophenyl)methyl]-N,N-diethyl-3-piperidinecarboxamide | [no description available] | medium | 1 | 0 | piperidines | |
| 1-(2,6-dimethyl-1-piperidinyl)-2-phenylethanone | [no description available] | medium | 1 | 0 | acetamides | |
| 2-amino-7-methyl-5-oxo-4-(2,3,4-trimethoxyphenyl)-4,6,7,8-tetrahydro-1-benzopyran-3-carbonitrile | [no description available] | medium | 1 | 0 | methoxybenzenes | |
| 3-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-phenylpyrrolidine-2,5-dione | [no description available] | medium | 1 | 0 | pyrrolidines | |
| 1-(4-bromophenyl)-3-(diethylamino)pyrrolidine-2,5-dione | [no description available] | medium | 1 | 0 | pyrrolidines | |
| 4-(5,6-diphenyl-1,2,4-triazin-3-yl)morpholine | [no description available] | medium | 1 | 0 | dialkylarylamine; tertiary amino compound | |
| (3,5-Dimethyl-1-adamantyl)amine nitrate | [no description available] | medium | 1 | 0 | nitrates | |
| 1-(4-tert-butylphenoxy)-3-(1H-1,2,4-triazol-5-ylthio)-2-propanol | [no description available] | medium | 1 | 0 | alkylbenzene | |
| N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-2-adamantanamine | [no description available] | medium | 1 | 0 | N-alkylpyrrolidine | |
| 4-phenyl-N-(pyridin-4-ylmethyl)-2-butanamine | [no description available] | medium | 1 | 0 | aralkylamine | |
| N-(5-nitro-2-pyridinyl)cyclopropanecarboxamide | [no description available] | medium | 1 | 0 | aromatic amide | |
| 3-[(4-bromophenyl)methyl]-4-(4-methoxyanilino)-4-oxobutanoic acid | [no description available] | medium | 1 | 0 | anilide | |
| 3-ethyl-N-(2H-tetrazol-5-yl)-1-adamantanecarboxamide | [no description available] | medium | 1 | 0 | aromatic amide | |
| N-(4-propan-2-ylphenyl)-3-bicyclo[2.2.1]heptanecarboxamide | [no description available] | medium | 1 | 0 | monoterpenoid | |
| 4-chloro-N-[2-(4-nitroanilino)ethyl]benzamide | [no description available] | medium | 1 | 0 | carbonyl compound; organohalogen compound | |
| 2-[(2,3-dihydro-1,4-benzodioxin-6-ylamino)-oxomethyl]-1-cyclohexanecarboxylic acid | [no description available] | medium | 1 | 0 | benzodioxine | |
| 2,4-dichloro-6-[1-(4-morpholinyl)-3-phenylprop-2-ynyl]phenol | [no description available] | medium | 1 | 0 | aromatic compound | |
| 2-[[1-(4-ethoxyphenyl)-2,5-dioxo-3-pyrrolidinyl]amino]acetonitrile | [no description available] | medium | 1 | 0 | pyrrolidines | |
| 1-ethoxy-3-(2-methoxy-4-prop-2-enylphenoxy)-2-propanol | [no description available] | medium | 1 | 0 | methoxybenzenes | |
| 6-amino-4-(3-chlorophenyl)-3-methyl-1-(phenylmethyl)-4H-pyrano[2,3-c]pyrazole-5-carbonitrile | [no description available] | medium | 1 | 0 | organochlorine compound; pyranopyrazole | |
| 1-(2-chlorophenoxy)-3-(2-methyl-1-benzimidazolyl)-2-propanol | [no description available] | medium | 1 | 0 | benzimidazoles | |
| N-[2-furanyl-(8-hydroxy-7-quinolinyl)methyl]-2-methylpropanamide | [no description available] | medium | 1 | 0 | hydroxyquinoline | |
| N-(2-hydroxy-5-methylphenyl)-2-furancarboxamide | [no description available] | medium | 1 | 0 | aromatic amide; furans | |
| 4-amino-7,8,9,10-tetrahydro-6H-pyrimido[3,4]pyrrolo[3,5-a]azepine-11-carbonitrile | [no description available] | medium | 1 | 0 | organic heterobicyclic compound; organonitrogen heterocyclic compound | |
| 1-(3,5-dimethylphenyl)-3-(1H-1,2,4-triazol-5-ylthio)pyrrolidine-2,5-dione | [no description available] | medium | 1 | 0 | pyrrolidines | |
| 6-[(3,4-difluoroanilino)-oxomethyl]-1-cyclohex-3-enecarboxylic acid | [no description available] | medium | 1 | 0 | anilide | |
| 4-[(3-cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)amino]-4-oxobutanoic acid | [no description available] | medium | 1 | 0 | organosulfur heterocyclic compound | |
| [3-methyl-4-[oxo(thiophen-2-yl)methyl]-1-piperazinyl]-thiophen-2-ylmethanone | [no description available] | medium | 1 | 0 | aromatic amide; thiophenes | |
| [4-(2-methoxyphenyl)-1-piperazinyl]-[4-[(phenylthio)methyl]phenyl]methanone | [no description available] | medium | 1 | 0 | piperazines | |
| N-(3,3,5-trimethylcyclohexyl)-1H-1,2,4-triazole-5-carboxamide | [no description available] | medium | 1 | 0 | aromatic amide; heteroarene | |
| 4-[2-nitro-5-[4-(phenylmethyl)sulfonyl-1-piperazinyl]phenyl]morpholine | [no description available] | medium | 1 | 0 | piperazines | |
| 5-(4-ethylsulfonyl-1-piperazinyl)-2-nitro-N-(3-pyridinylmethyl)aniline | [no description available] | medium | 1 | 0 | piperazines | |
| 2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-methyl-1,2,4-triazol-3-yl]thio]-N-[2-(4-morpholinyl)ethyl]acetamide | [no description available] | medium | 1 | 0 | benzothiazoles | |
| N-ethyl-N-[2-[(5-nitro-8-quinolinyl)amino]ethyl]benzenesulfonamide | [no description available] | medium | 1 | 0 | nitro compound; quinolines | |
| 1-(4-methoxyphenyl)-N-(4-methyl-2-pyridinyl)-5-oxo-3-pyrrolidinecarboxamide | [no description available] | medium | 1 | 0 | pyrrolidines | |
| 3,4,5-trimethoxy-N-[4-[(2-methyl-1-piperidinyl)sulfonyl]phenyl]benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| 3-(n,n-dimethylsulfonamido)-4-methyl-nitrobenzene | [no description available] | medium | 1 | 0 | C-nitro compound; sulfonamide; toluenes | bone density conservation agent; EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor; geroprotector |
| 6,3',4'-Trimethoxyflavanone | [no description available] | medium | 1 | 0 | ether; flavonoids | |
| 1-[4-(3-ethoxyphenoxy)butyl]imidazole | [no description available] | medium | 1 | 0 | aromatic ether | |
| 5-[[(1-cyclohexyl-5-tetrazolyl)thio]methyl]-3-phenyl-1,2,4-oxadiazole | [no description available] | medium | 1 | 0 | oxadiazole; ring assembly | |
| 2-[1-(3,4-dihydro-2H-quinolin-1-yl)-1-oxopropan-2-yl]isoindole-1,3-dione | [no description available] | medium | 1 | 0 | phthalimides | |
| [4-(benzenesulfonyl)-1-piperazinyl]-(1-piperidinyl)methanone | [no description available] | medium | 1 | 0 | sulfonamide | |
| 3-(2,5-dioxo-1-pyrrolidinyl)-N-(2-methyl-1,3-dioxo-5-isoindolyl)benzamide | [no description available] | medium | 1 | 0 | amidobenzoic acid | |
| 6-[[[5-(ethylthio)-1,3,4-thiadiazol-2-yl]amino]-oxomethyl]-1-cyclohex-3-enecarboxylic acid | [no description available] | medium | 1 | 0 | aromatic amide | |
| 2,5-dimethoxy-n-(quinolin-3-yl)benzenesulfonamide | [no description available] | medium | 1 | 0 | quinolines | |
| LSM-25805 | [no description available] | medium | 1 | 0 | isoindoles | |
| 4-ethoxy-N-(3-quinolinyl)benzenesulfonamide | [no description available] | medium | 1 | 0 | quinolines | |
| 3-chloro-N-[3-(1-imidazolyl)propyl]-6-nitro-1-benzothiophene-2-carboxamide | [no description available] | medium | 1 | 0 | 1-benzothiophenes | |
| nsc 727447 | [no description available] | medium | 1 | 0 | ||
| 2-methoxy-N-[(4-methylphenyl)methyl]-2-phenylacetamide | [no description available] | medium | 1 | 0 | acetamides | |
| 2-(4-chlorophenoxy)-N-(5-nitro-2-thiazolyl)acetamide | [no description available] | medium | 1 | 0 | C-nitro compound; thiazoles | |
| 7-(2-methoxyphenyl)-5-phenyl-1,7-dihydrotetrazolo[1,5-a]pyrimidine | [no description available] | medium | 1 | 0 | methoxybenzenes | |
| N-[3-[2,5-dioxo-3-(phenylmethyl)-1-pyrrolidinyl]phenyl]acetamide | [no description available] | medium | 1 | 0 | pyrrolidines | |
| 3,4-dimethoxy-N-[3-(methylthio)phenyl]benzenesulfonamide | [no description available] | medium | 1 | 0 | sulfonamide | |
| 3-methyl-4-nitro-N-(1H-1,2,4-triazol-5-yl)benzamide | [no description available] | medium | 1 | 0 | C-nitro compound | |
| 2-[(4-chlorophenyl)methylthio]-N-(2-hydroxy-5-nitrophenyl)acetamide | [no description available] | medium | 1 | 0 | nitrophenol | |
| 2-(4-ethoxyphenyl)-N-[3-(1-imidazolyl)propyl]-4-quinolinecarboxamide | [no description available] | medium | 1 | 0 | quinolines | |
| N-(4-bromophenyl)-5-methyl-4-nitro-1H-pyrazol-3-amine | [no description available] | medium | 1 | 0 | C-nitro compound | |
| 3,3-bis(4-hydroxyphenyl)-7-methyl-1,3-dihydro-2h-indol-2-one | [no description available] | medium | 1 | 0 | ||
| N-[4-[(cyclohexylamino)-oxomethyl]phenyl]-3-pyridinecarboxamide | [no description available] | medium | 1 | 0 | aromatic amide | |
| N,N,4-trimethyl-2-[[(5-methyl-2-furanyl)-oxomethyl]amino]-5-thiazolecarboxamide | [no description available] | medium | 1 | 0 | aromatic amide; thiazoles | |
| ex 527 | [no description available] | medium | 1 | 0 | carbazoles; monocarboxylic acid amide; organochlorine compound | |
| 3-[3-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]propyl]-1H-benzimidazol-2-one | [no description available] | medium | 1 | 0 | indoles | |
| 4-methyl-2,7-diphenyl-8H-pyrido[2,3-d]pyrimidin-5-one | [no description available] | medium | 1 | 0 | phenylpyridine | |
| 3-methylharman | [no description available] | medium | 1 | 0 | ||
| 1-methyl-beta-carboline-3-carboxylic acid | [no description available] | medium | 1 | 0 | ||
| sildenafil | [no description available] | medium | 1 | 0 | piperazines; pyrazolopyrimidine; sulfonamide | EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor; vasodilator agent |
| 2-methyl-4(3h)-quinazolinone | [no description available] | medium | 1 | 0 | ||
| n(4)-desoxychlordiazepoxide | [no description available] | medium | 1 | 0 | ||
| 2-amino-3-hydroxyphenazine | [no description available] | medium | 1 | 0 | ||
| 2-styrylquinazolin-4(3h)-one | [no description available] | medium | 1 | 0 | ||
| 2-amino-5-iodo-6-phenyl-4-pyrimidinone | [no description available] | medium | 1 | 0 | ||
| quininib | [no description available] | medium | 1 | 0 | phenols; styrylquinoline | angiogenesis inhibitor |
| bropirimine | [no description available] | medium | 1 | 0 | pyrimidines | |
| 2-[(6-ethyl-4-methyl-2-quinazolinyl)amino]-1H-quinazolin-4-one | [no description available] | medium | 1 | 0 | quinazolines | |
| 2-[(6-ethyl-4-methyl-2-quinazolinyl)amino]-6-(methoxymethyl)-1H-pyrimidin-4-one | [no description available] | medium | 1 | 0 | quinazolines | |
| dimethylphenylpiperazinium iodide | [no description available] | low | 0 | 0 | piperazines | |
| 1-(2-methoxyphenyl)piperazine | [no description available] | low | 0 | 0 | piperazines | |
| bmy 7378 | [no description available] | low | 0 | 0 | piperazines | |
| cetirizine | [no description available] | low | 0 | 0 | ether; monocarboxylic acid; monochlorobenzenes; piperazines | anti-allergic agent; environmental contaminant; H1-receptor antagonist; xenobiotic |
| dipropizine | [no description available] | low | 0 | 0 | piperazines | |
| itraconazole | [no description available] | low | 0 | 0 | piperazines | |
| 5-isoquinolinesulfonic acid [4-[2-[5-isoquinolinylsulfonyl(methyl)amino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl] ester | [no description available] | low | 0 | 0 | piperazines | |
| naftopidil | [no description available] | low | 0 | 0 | piperazines | |
| piperazine | [no description available] | low | 0 | 0 | azacycloalkane; piperazines; saturated organic heteromonocyclic parent | anthelminthic drug |
| prazosin | [no description available] | low | 0 | 0 | aromatic ether; furans; monocarboxylic acid amide; piperazines; quinazolines | alpha-adrenergic antagonist; antihypertensive agent; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor |
| quipazine | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| terazosin | [no description available] | low | 0 | 0 | furans; piperazines; primary amino compound; quinazolines | alpha-adrenergic antagonist; antihypertensive agent; antineoplastic agent |
| urapidil | [no description available] | low | 0 | 0 | piperazines | |
| n-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-n-(2-pyridinyl)cyclohexanecarboxamide | [no description available] | low | 0 | 0 | piperazines | |
| [4-(2-pyridinyl)-1-piperazinyl]-(3,4,5-trimethoxyphenyl)methanone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| almitrine | [no description available] | low | 0 | 0 | piperazines; triamino-1,3,5-triazine | central nervous system stimulant |
| etoperidone | [no description available] | low | 0 | 0 | piperazines | |
| ziprasidone | [no description available] | low | 0 | 0 | 1,2-benzisothiazole; indolones; organochlorine compound; piperazines | antipsychotic agent; dopaminergic antagonist; histamine antagonist; muscarinic antagonist; psychotropic drug; serotonergic antagonist |
| antrafenine | [no description available] | low | 0 | 0 | piperazines | |
| mepiprazole | [no description available] | low | 0 | 0 | piperazines | |
| niaprazine | [no description available] | low | 0 | 0 | piperazines | |
| way 100135 | [no description available] | low | 0 | 0 | piperazines | |
| bp 554 | [no description available] | low | 0 | 0 | piperazines | |
| gr 144053 | [no description available] | low | 0 | 0 | piperazines | |
| 2-[4-(4-methoxyphenyl)-1-piperazinyl]pyrimidine | [no description available] | low | 0 | 0 | piperazines | |
| 2-(4-methyl-1-piperazinyl)aniline | [no description available] | low | 0 | 0 | piperazines | |
| ar-c239 | [no description available] | low | 0 | 0 | piperazines | |
| 2-[2-[4-(2-fluorophenyl)-1-piperazinyl]-2-oxoethyl]-1,1-dioxo-1,2-benzothiazol-3-one | [no description available] | low | 0 | 0 | piperazines | |
| 2-[(5,5-dimethyl-6H-[1,2,4]triazolo[3,4-a]isoquinolin-3-yl)thio]-1-[4-(2-methoxyphenyl)-1-piperazinyl]ethanone | [no description available] | low | 0 | 0 | piperazines | |
| 1-[(1-tert-butyl-5-tetrazolyl)-thiophen-2-ylmethyl]-4-(2,3-dimethylphenyl)piperazine | [no description available] | low | 0 | 0 | piperazines | |
| 3-chloro-1-cyclohexyl-4-(4-methyl-1-piperazinyl)pyrrole-2,5-dione | [no description available] | low | 0 | 0 | maleimides; piperazines | |
| N-[4-[3-[4-(5-chloro-2-methylphenyl)-1-piperazinyl]-2-hydroxypropoxy]phenyl]acetamide | [no description available] | low | 0 | 0 | piperazines | |
| 4-[4-[[1-[(4-methoxyphenyl)methyl]-5-tetrazolyl]-(3-pyridinyl)methyl]-1-piperazinyl]phenol | [no description available] | low | 0 | 0 | piperazines | |
| 1-[1-(1-cyclopentyl-5-tetrazolyl)-2-methylpropyl]-4-(2-fluorophenyl)piperazine | [no description available] | low | 0 | 0 | piperazines | |
| 3-[(1-cyclopentyl-5-tetrazolyl)-[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-7-methyl-1H-quinolin-2-one | [no description available] | low | 0 | 0 | piperazines | |
| 1-methyl-4-[2-oxo-2-(4-phenyl-1-piperazinyl)ethyl]-5-pyrrolo[3,2-b]pyrrolecarboxylic acid ethyl ester | [no description available] | low | 0 | 0 | piperazines | |
| 6-methyl-2-[4-[oxo(thiophen-2-yl)methyl]-1-piperazinyl]-3-quinolinecarbonitrile | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| [5-(2-furanyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinyl]-[4-(2-pyridinyl)-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 1-(4-fluorophenyl)-4-[[1-(2-phenylethyl)-5-tetrazolyl]-thiophen-2-ylmethyl]piperazine | [no description available] | low | 0 | 0 | piperazines | |
| 6,7-dimethoxy-2-[[2-[4-(4-methoxyphenyl)-1-piperazinyl]-2-oxoethyl]thio]-3-quinolinecarbonitrile | [no description available] | low | 0 | 0 | piperazines | |
| 1-[4-(2-methoxyphenyl)-1-piperazinyl]-2-[[5-(2-methyl-3-furanyl)-1,3,4-oxadiazol-2-yl]thio]ethanone | [no description available] | low | 0 | 0 | piperazines | |
| 1-[1-[1-(1,3-benzodioxol-5-ylmethyl)-5-tetrazolyl]-2-methylpropyl]-4-phenylpiperazine | [no description available] | low | 0 | 0 | piperazines | |
| 2-[(5,5-dimethyl-6H-[1,2,4]triazolo[3,4-a]isoquinolin-3-yl)thio]-1-(4-phenyl-1-piperazinyl)ethanone | [no description available] | low | 0 | 0 | piperazines | |
| 3-chloro-4-[4-(4-fluorophenyl)sulfonyl-1-piperazinyl]-N,N-dimethylbenzenesulfonamide | [no description available] | low | 0 | 0 | piperazines | |
| 2-(3-methylphenoxy)-N-[4-(4-methylsulfonyl-1-piperazinyl)phenyl]acetamide | [no description available] | low | 0 | 0 | piperazines | |
| 1-(2-methoxyphenyl)-4-[(4-methylphenyl)-(1-propan-2-yl-5-tetrazolyl)methyl]piperazine | [no description available] | low | 0 | 0 | piperazines | |
| 4-[4-[(1-cyclopentyl-5-tetrazolyl)-pyridin-4-ylmethyl]-1-piperazinyl]phenol | [no description available] | low | 0 | 0 | piperazines | |
| 5,8-dimethoxy-4-(4-methyl-1-piperazinyl)-2-(trifluoromethyl)quinoline | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 1-phenyl-4-[[1-(phenylmethyl)-5-tetrazolyl]-(3-pyridinyl)methyl]piperazine | [no description available] | low | 0 | 0 | piperazines | |
| 1-[(3,4-dimethoxyphenyl)-[1-(thiophen-2-ylmethyl)-5-tetrazolyl]methyl]-4-phenylpiperazine | [no description available] | low | 0 | 0 | piperazines | |
| 1-[(1-cyclopentyl-5-tetrazolyl)-thiophen-2-ylmethyl]-4-(2-methoxyphenyl)piperazine | [no description available] | low | 0 | 0 | piperazines | |
| 1-[(2-methoxyphenyl)-[1-(2-phenylethyl)-5-tetrazolyl]methyl]-4-phenylpiperazine | [no description available] | low | 0 | 0 | piperazines | |
| 2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thio]-1-(4-phenyl-1-piperazinyl)ethanone | [no description available] | low | 0 | 0 | piperazines | |
| 8-(2-furanyl)-6-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-3,3-dimethyl-1,4-dihydrothiopyrano[3,4-c]pyridine-5-carbonitrile | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 3-[[2-[4-(3-chlorophenyl)-1-piperazinyl]-1-oxoethyl]amino]-1H-indole-2-carboxylic acid methyl ester | [no description available] | low | 0 | 0 | piperazines | |
| 1-[(4-methylphenyl)methyl]-4-[4-(4-methylphenyl)-1-piperazinyl]pyrazolo[3,4-d]pyrimidine | [no description available] | low | 0 | 0 | piperazines | |
| 7-hexyl-3-methyl-8-(4-phenyl-1-piperazinyl)purine-2,6-dione | [no description available] | low | 0 | 0 | piperazines | |
| 8-[4-(3-chlorophenyl)-1-piperazinyl]-3-methyl-7-pentylpurine-2,6-dione | [no description available] | low | 0 | 0 | piperazines | |
| 6-hydroxy-7-phenyl-4-[(4-phenyl-1-piperazinyl)methyl]-1-benzopyran-2-one | [no description available] | low | 0 | 0 | piperazines | |
| 7-(3-chlorophenyl)-2-(4-phenyl-1-piperazinyl)-7,8-dihydro-6H-quinazolin-5-one | [no description available] | low | 0 | 0 | piperazines | |
| N-[1-methyl-2-[2-(4-phenyl-1-piperazinyl)ethyl]-5-benzimidazolyl]-2-furancarboxamide | [no description available] | low | 0 | 0 | piperazines | |
| 7-butyl-8-[[4-(3-chlorophenyl)-1-piperazinyl]methyl]-1,3-dimethylpurine-2,6-dione | [no description available] | low | 0 | 0 | piperazines | |
| 2-methyl-3-phenyl-5-propyl-7-[4-(2-pyridinyl)-1-piperazinyl]pyrazolo[1,5-a]pyrimidine | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| N2-(4-fluorophenyl)-6-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-1,3,5-triazine-2,4-diamine | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 4-(3,4-dihydro-2H-quinolin-1-yl)-6-[(4-phenyl-1-piperazinyl)methyl]-1,3,5-triazin-2-amine | [no description available] | low | 0 | 0 | piperazines | |
| 8-[[4-(4-fluorophenyl)-1-piperazinyl]methyl]-1,3-dimethyl-7-[2-(4-morpholinyl)ethyl]purine-2,6-dione | [no description available] | low | 0 | 0 | piperazines | |
| 5-[(2-chloro-6-fluorophenyl)methyl]-N-[2-[4-(4-methoxyphenyl)-1-piperazinyl]ethyl]-1,3,4-oxadiazole-2-carboxamide | [no description available] | low | 0 | 0 | piperazines | |
| (3,4-dimethylphenyl)-(4-phenyl-1-piperazinyl)methanone | [no description available] | low | 0 | 0 | piperazines | |
| 4-(4-propan-2-yl-1-piperazinyl)phenol | [no description available] | low | 0 | 0 | piperazines | |
| 1-(2,4-dimethylphenyl)-4-(1-piperidinylsulfonyl)piperazine | [no description available] | low | 0 | 0 | piperazines | |
| 1-[4-(4-aminophenyl)-1-piperazinyl]ethanone | [no description available] | low | 0 | 0 | piperazines | |
| 1-[(4-phenyl-1-piperazinyl)methyl]-2-naphthalenol | [no description available] | low | 0 | 0 | piperazines | |
| [4-(2-methylphenyl)-1-piperazinyl]-(4-nitrophenyl)methanethione | [no description available] | low | 0 | 0 | piperazines | |
| 4-(methoxymethyl)-6-methyl-2-(4-phenyl-1-piperazinyl)-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 1-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-2-benzo[cd]indolone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 1-[4-(2,3-dimethylphenyl)-1-piperazinyl]-2-methyl-1-propanone | [no description available] | low | 0 | 0 | piperazines | |
| 1,3-benzothiazol-2-yl-[4-(2-pyridinyl)-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 1,3-dimethyl-8-(4-phenyl-1-piperazinyl)-7H-purine-2,6-dione | [no description available] | low | 0 | 0 | piperazines | |
| 2-[[2-[4-(4-chlorophenyl)-1-piperazinyl]-2-oxoethyl]thio]-3-ethyl-4-quinazolinone | [no description available] | low | 0 | 0 | piperazines | |
| 2-[[5-[(2,6-dimethylphenoxy)methyl]-4-ethyl-1,2,4-triazol-3-yl]thio]-1-(4-phenyl-1-piperazinyl)ethanone | [no description available] | low | 0 | 0 | piperazines | |
| 6-(4-benzoyl-1-piperazinyl)-3,3-dimethyl-8-propan-2-yl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| N-(3,5-dimethylphenyl)-4-(3-methoxyphenyl)-1-piperazinecarbothioamide | [no description available] | low | 0 | 0 | piperazines | |
| 2-(4-chlorophenoxy)-N-[4-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]phenyl]acetamide | [no description available] | low | 0 | 0 | piperazines | |
| N-[4-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]phenyl]-2-(3-methylphenoxy)acetamide | [no description available] | low | 0 | 0 | piperazines | |
| N-[4-[4-[(2-methylphenyl)-oxomethyl]-1-piperazinyl]phenyl]propanamide | [no description available] | low | 0 | 0 | piperazines | |
| [3-amino-4-(methoxymethyl)-6-methyl-2-thieno[2,3-b]pyridinyl]-(4-phenyl-1-piperazinyl)methanone | [no description available] | low | 0 | 0 | piperazines | |
| [4-(2-methoxyphenyl)-1-piperazinyl]-[5-(4-methylphenyl)-3-isoxazolyl]methanone | [no description available] | low | 0 | 0 | piperazines | |
| 1-(3,4-dimethoxyphenyl)sulfonyl-4-(2-methoxyphenyl)piperazine | [no description available] | low | 0 | 0 | piperazines | |
| 2-[2-[4-(4-fluorophenyl)-1-piperazinyl]-2-oxoethoxy]benzoic acid methyl ester | [no description available] | low | 0 | 0 | piperazines | |
| 1-[1-ethyl-4-[4-(4-methoxyphenyl)-1-piperazinyl]-6-methyl-2-sulfanylidene-5-pyrimidinyl]ethanone | [no description available] | low | 0 | 0 | piperazines | |
| [4-(4-fluorophenyl)-1-piperazinyl]-(2-methyl-3-pyrazolyl)methanone | [no description available] | low | 0 | 0 | piperazines | |
| [4-(2-methylphenyl)-1-piperazinyl]-(5-propyl-3-thiophenyl)methanone | [no description available] | low | 0 | 0 | piperazines | |
| (4-chlorophenyl)-[4-(7-chloro-4-quinolinyl)-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 2-(4-chloro-3,5-dimethylphenoxy)-N-[4-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]phenyl]acetamide | [no description available] | low | 0 | 0 | piperazines | |
| N-[2-(4-acetyl-1-piperazinyl)phenyl]-2-(5-methyl-2-propan-2-ylphenoxy)acetamide | [no description available] | low | 0 | 0 | piperazines | |
| 1-(3,4-dimethoxyphenyl)sulfonyl-4-(2,6-dimethylphenyl)piperazine | [no description available] | low | 0 | 0 | piperazines | |
| [4-(2,3-dimethylphenyl)-1-piperazinyl]-(3,4,5-trimethoxyphenyl)methanone | [no description available] | low | 0 | 0 | piperazines | |
| 2-(1-imidazolyl)-4-phenyl-6-(4-phenyl-1-piperazinyl)-1,3,5-triazine | [no description available] | low | 0 | 0 | piperazines | |
| 7-chloro-4-[4-(3,4-dimethylphenyl)sulfonyl-1-piperazinyl]quinoline | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 1-[1-ethyl-4-[4-(4-fluorophenyl)-1-piperazinyl]-6-methyl-2-sulfanylidene-5-pyrimidinyl]ethanone | [no description available] | low | 0 | 0 | piperazines | |
| N-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester | [no description available] | low | 0 | 0 | piperazines | |
| 1-[1-ethyl-6-methyl-4-(4-phenyl-1-piperazinyl)-2-sulfanylidene-5-pyrimidinyl]ethanone | [no description available] | low | 0 | 0 | piperazines | |
| 4-[[4-(2,3-dimethylphenyl)-1-piperazinyl]methyl]-2,6-dimethoxyphenol | [no description available] | low | 0 | 0 | piperazines | |
| 2-[5-(2-aminophenyl)-2-tetrazolyl]-1-[4-(4-methoxyphenyl)-1-piperazinyl]ethanone | [no description available] | low | 0 | 0 | piperazines | |
| 2-[4-(2-methoxyphenyl)-1-piperazinyl]-N-[4-(1-tetrazolyl)phenyl]acetamide | [no description available] | low | 0 | 0 | piperazines | |
| 7-methoxy-2-[4-[(2-methylphenyl)-oxomethyl]-1-piperazinyl]-3-quinolinecarbonitrile | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 5-cyano-2-phenyl-6-[4-(2-pyridinyl)-1-piperazinyl]-3-pyridinecarboxylic acid ethyl ester | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 1-[(4-methylphenyl)methyl]-4-[4-(2-methylphenyl)-1-piperazinyl]pyrazolo[3,4-d]pyrimidine | [no description available] | low | 0 | 0 | piperazines | |
| 1-[(4-chlorophenyl)methyl]-4-[4-(2-methylphenyl)-1-piperazinyl]pyrazolo[3,4-d]pyrimidine | [no description available] | low | 0 | 0 | piperazines | |
| 4-[4-(3-chlorophenyl)-1-piperazinyl]aniline | [no description available] | low | 0 | 0 | piperazines | |
| N-[(2-furanylmethylamino)-oxomethyl]-2-[4-(4-hydroxyphenyl)-1-piperazinyl]acetamide | [no description available] | low | 0 | 0 | piperazines | |
| N-[(tert-butylamino)-oxomethyl]-2-[4-(4-hydroxyphenyl)-1-piperazinyl]acetamide | [no description available] | low | 0 | 0 | piperazines | |
| N-[(tert-butylamino)-oxomethyl]-2-[4-(3-chlorophenyl)-1-piperazinyl]acetamide | [no description available] | low | 0 | 0 | piperazines | |
| 4-(4-hydroxyphenyl)-N-(phenylmethyl)-1-piperazinecarbothioamide | [no description available] | low | 0 | 0 | piperazines | |
| [4-(5-chloro-2-methylphenyl)-1-piperazinyl]-(2-ethoxy-3-pyridinyl)methanone | [no description available] | low | 0 | 0 | piperazines | |
| 1-[[4-(2,4,6-trimethylphenyl)-1-piperazinyl]sulfonyl]azepane | [no description available] | low | 0 | 0 | piperazines | |
| [4-(2-ethoxyphenyl)-1-piperazinyl]-(1-oxido-4-pyridin-1-iumyl)methanone | [no description available] | low | 0 | 0 | piperazines | |
| 3-[(4-chlorophenyl)thio]-1-[4-(4-hydroxyphenyl)-1-piperazinyl]-1-propanone | [no description available] | low | 0 | 0 | piperazines | |
| 1-[4-(4-hydroxyphenyl)-1-piperazinyl]-3-(1H-indol-3-yl)-1-propanone | [no description available] | low | 0 | 0 | piperazines | |
| 3-[[4-(2,3-dimethylphenyl)-1-piperazinyl]-oxomethyl]-N,N-dimethyl-4-(1-pyrrolidinyl)benzenesulfonamide | [no description available] | low | 0 | 0 | piperazines | |
| [4-(4-hydroxyphenyl)-1-piperazinyl]-[2-methoxy-4-(methylthio)phenyl]methanone | [no description available] | low | 0 | 0 | piperazines | |
| 2-(2,3-dihydro-1H-inden-5-yloxy)-1-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethanone | [no description available] | low | 0 | 0 | piperazines | |
| N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-2-[4-(4-hydroxyphenyl)-1-piperazinyl]acetamide | [no description available] | low | 0 | 0 | piperazines | |
| 3-[[4-(4-fluorophenyl)-1-piperazinyl]sulfonyl]benzoic acid [2-(methylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | piperazines | |
| 2-chloro-N-(2,3-dihydro-1H-inden-5-yl)-5-[(4-phenyl-1-piperazinyl)sulfonyl]benzamide | [no description available] | low | 0 | 0 | piperazines | |
| 2-[4-(2-hydroxyphenyl)-1-piperazinyl]-N-(5-methyl-3-isoxazolyl)acetamide | [no description available] | low | 0 | 0 | piperazines | |
| N-[(cyclopentylamino)-oxomethyl]-2-[4-(2-hydroxyphenyl)-1-piperazinyl]acetamide | [no description available] | low | 0 | 0 | piperazines | |
| [4-(3-chlorophenyl)-1-piperazinyl]-(2,5-dimethyl-3-furanyl)methanone | [no description available] | low | 0 | 0 | piperazines | |
| 3-[3-[4-(3-chlorophenyl)-1-piperazinyl]-3-oxopropyl]-4-pyrido[2,3-d]pyrimidinone | [no description available] | low | 0 | 0 | piperazines | |
| Ethyl 4-(2-methoxyphenyl)piperazine-1-carboxylate | [no description available] | low | 0 | 0 | piperazines | |
| N-tert-butyl-4-[3-(trifluoromethyl)-2-pyridinyl]-1-piperazinecarboxamide | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 2-amino-6-[4-(6-chloro-2-pyridinyl)-1-piperazinyl]pyridine-3,5-dicarbonitrile | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| (3,5-dichlorophenyl)-[4-[2-(trifluoromethyl)-4-quinolinyl]-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| (4-methylphenyl)-[4-[4-nitro-2-(1-pyrrolyl)phenyl]-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines | |
| N-(4-butyl-2-methylphenyl)-N'-[4-(4-methylpiperazino)phenyl]urea | [no description available] | low | 0 | 0 | piperazines | |
| 2-({2-[4-(4-Fluorophenyl)piperazino]-2-oxoethyl}sulfanyl)acetic acid | [no description available] | low | 0 | 0 | piperazines | |
| 3-[5-[[4-(2-pyridinyl)-1-piperazinyl]sulfonyl]-2-thiophenyl]isoxazole | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 4-[4-(3-bromophenyl)sulfonyl-1-piperazinyl]-7-chloroquinoline | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 3-[4-(4-chlorophenyl)-1-piperazinyl]-1-(4-methoxyphenyl)pyrrolidine-2,5-dione | [no description available] | low | 0 | 0 | piperazines | |
| 1-(4-fluorophenyl)-3-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]pyrrolidine-2,5-dione | [no description available] | low | 0 | 0 | piperazines | |
| 1-(5-bicyclo[2.2.1]hept-2-enylmethyl)-4-[3-(trifluoromethyl)phenyl]piperazine | [no description available] | low | 0 | 0 | piperazines | |
| N-[2-(4-chlorophenoxy)ethyl]-5-(3,5-dimethyl-1-piperazinyl)-2-nitroaniline | [no description available] | low | 0 | 0 | piperazines | |
| 3,7-dimethyl-2-[4-(2-pyridinyl)-1-piperazinyl]quinoline | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 3-[2-[4-(2-chloro-4-nitrophenyl)-1-piperazinyl]ethoxy]-4-phenyl-1,2,5-oxadiazole | [no description available] | low | 0 | 0 | piperazines | |
| 3-phenyl-1-[4-(2-pyridinyl)-1-piperazinyl]-1-propanone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 1-[2-nitro-4-(trifluoromethylsulfonyl)phenyl]-4-phenylpiperazine | [no description available] | low | 0 | 0 | piperazines | |
| N-[[4-(4-nitrophenyl)-1-piperazinyl]-sulfanylidenemethyl]butanamide | [no description available] | low | 0 | 0 | piperazines | |
| N-cyclohexyl-4-(4-nitrophenyl)-1-piperazinecarbothioamide | [no description available] | low | 0 | 0 | piperazines | |
| 6-amino-4-[3-[[4-(4-fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | [no description available] | low | 0 | 0 | piperazines; pyranopyrazole | |
| N-(4-fluorophenyl)-4-(4-nitrophenyl)-1-piperazinecarbothioamide | [no description available] | low | 0 | 0 | piperazines | |
| 1-adamantyl-[4-(2-fluorophenyl)-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines | |
| 2-[4-(4-nitrophenyl)-1-piperazinyl]-N-(2-pyridinyl)acetamide | [no description available] | low | 0 | 0 | piperazines | |
| N-(2-adamantyl)-4-(4-ethylsulfonyl-1-piperazinyl)-3-nitrobenzamide | [no description available] | low | 0 | 0 | piperazines | |
| 4-phenoxy-1-[4-(2-pyridinyl)-1-piperazinyl]-1-butanone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 1-(3,4-dichlorophenyl)sulfonyl-4-[3-[(4-methyl-1,2,4-triazol-3-yl)thio]-4-nitrophenyl]piperazine | [no description available] | low | 0 | 0 | piperazines | |
| N-[3-chloro-4-[4-[oxo-(4-propoxyphenyl)methyl]-1-piperazinyl]phenyl]propanamide | [no description available] | low | 0 | 0 | piperazines | |
| 4-(4-nitrophenyl)-N-prop-2-enyl-1-piperazinecarbothioamide | [no description available] | low | 0 | 0 | piperazines | |
| 3-fluoro-N-[4-[[4-(4-methoxyphenyl)-1-piperazinyl]-oxomethyl]phenyl]benzenesulfonamide | [no description available] | low | 0 | 0 | piperazines | |
| 1-[3-[4-(2-chloro-5-methoxyphenyl)-1-piperazinyl]propyl]-3-(4-methylphenyl)urea | [no description available] | low | 0 | 0 | piperazines | |
| 1-(4-methoxy-2-nitrophenyl)-4-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)piperazine | [no description available] | low | 0 | 0 | piperazines | |
| 2-[4-(2-methyl-4-quinolinyl)-1-piperazinyl]-4-phenylthiazole | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| N-[3-chloro-4-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]phenyl]-2-(4-chlorophenyl)acetamide | [no description available] | low | 0 | 0 | piperazines | |
| 2-(4-chlorophenyl)-N-[4-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]phenyl]acetamide | [no description available] | low | 0 | 0 | piperazines | |
| 2-[3-oxo-1-[[[oxo(thiophen-2-yl)methyl]amino]-sulfanylidenemethyl]-2-piperazinyl]acetic acid propan-2-yl ester | [no description available] | low | 0 | 0 | isopropyl ester; piperazines | |
| 2-[1-[[[(4-methoxyphenyl)-oxomethyl]amino]-sulfanylidenemethyl]-3-oxo-2-piperazinyl]acetic acid propan-2-yl ester | [no description available] | low | 0 | 0 | isopropyl ester; piperazines | |
| 1-(1,3-benzodioxol-5-yl)-3-[4-(4-hydroxyphenyl)-1-piperazinyl]pyrrolidine-2,5-dione | [no description available] | low | 0 | 0 | piperazines | |
| 4-(diethylamino)benzoic acid [2-oxo-2-(4-phenyl-1-piperazinyl)ethyl] ester | [no description available] | low | 0 | 0 | piperazines | |
| 2-chloro-N-[5-chloro-2-(4-methyl-1-piperazinyl)phenyl]benzenesulfonamide | [no description available] | low | 0 | 0 | piperazines | |
| 7-[3-[4-(2-ethoxyphenyl)-1-piperazinyl]-2-hydroxypropoxy]-4-methyl-1-benzopyran-2-one | [no description available] | low | 0 | 0 | piperazines | |
| 3-[(4-phenyl-1-piperazinyl)sulfonyl]benzoic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | piperazines | |
| pramiconazole | [no description available] | low | 0 | 0 | piperazines | |
| 4-[4-[[1-(2-methylbutan-2-yl)-5-tetrazolyl]-(6-quinolinyl)methyl]-1-piperazinyl]phenol | [no description available] | low | 0 | 0 | piperazines | |
| 1-[3-methyl-1-[1-[(4-methylphenyl)sulfonylmethyl]-5-tetrazolyl]butyl]-4-phenylpiperazine | [no description available] | low | 0 | 0 | piperazines | |
| 2-[4-[4-(4-fluorophenyl)-2-thiazolyl]-1-piperazinyl]-1-[4-(4-methoxyphenyl)-1-piperazinyl]ethanone | [no description available] | low | 0 | 0 | piperazines | |
| 3-[(2-chlorophenyl)methyl]-7-[4-[4-(trifluoromethyl)phenyl]-1-piperazinyl]triazolo[4,5-d]pyrimidine | [no description available] | low | 0 | 0 | piperazines | |
| 4-[4-[(1-tert-butyl-5-tetrazolyl)-pyridin-4-ylmethyl]-1-piperazinyl]phenol | [no description available] | low | 0 | 0 | piperazines | |
| 2-[(3-fluorophenyl)methylthio]-1-(4-phenyl-1-piperazinyl)ethanone | [no description available] | low | 0 | 0 | piperazines | |
| 1-methyl-4-[[2-oxo-2-[4-(2-pyridinyl)-1-piperazinyl]ethyl]thio]-2-quinolinone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| N-[3-[4-(2,3-dimethylphenyl)-1-piperazinyl]-3-oxopropyl]-2-(1-oxo-2-isoquinolinyl)acetamide | [no description available] | low | 0 | 0 | piperazines | |
| 6-bromo-3-[4-oxo-4-[4-(2-pyridinyl)-1-piperazinyl]butyl]-2-sulfanylidene-1H-quinazolin-4-one | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 3-chloro-N-[2-[4-(4-fluorophenyl)-1-piperazinyl]-2-(3-pyridinyl)ethyl]benzamide | [no description available] | low | 0 | 0 | piperazines | |
| 1-(4-methyl-2-prop-2-enylphenoxy)-3-(4-phenyl-1-piperazinyl)-2-propanol | [no description available] | low | 0 | 0 | piperazines | |
| 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione | [no description available] | low | 0 | 0 | piperazines | |
| N-[4-[[4-(2-fluorophenyl)-1-piperazinyl]-oxomethyl]-1-oxo-2-isoquinolinyl]-2-pyrazinecarboxamide | [no description available] | low | 0 | 0 | piperazines | |
| N-[4-methyl-2-(4-methyl-1-piperazinyl)-6-quinolinyl]-1,3-benzodioxole-5-carboxamide | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 4-[2-(1-cyclohexenyl)ethyl]-1-cyclohexyl-3-pyridin-4-ylpiperazine-2,5-dione | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 2-[[3-oxo-2-[3-oxo-3-(4-phenyl-1-piperazinyl)propyl]-2H-imidazo[1,2-c]quinazolin-5-yl]thio]acetonitrile | [no description available] | low | 0 | 0 | piperazines | |
| [5-(3-chlorophenyl)-3-isoxazolyl]-[4-(2-methoxyphenyl)-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines | |
| 1-[3-[4-(2-fluorophenyl)-1-piperazinyl]propyl]-3-[4-(methylthio)phenyl]urea | [no description available] | low | 0 | 0 | piperazines | |
| ml012 | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| N-[2-[4-(3-chlorophenyl)-1-piperazinyl]ethyl]-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine | [no description available] | low | 0 | 0 | piperazines | |
| N-[2-[4-(4-fluorophenyl)-1-piperazinyl]-2-(3-pyridinyl)ethyl]cyclohexanecarboxamide | [no description available] | low | 0 | 0 | piperazines | |
| [4-(2-pyrimidinyl)-1-piperazinyl]-[1-[4-(2-pyrimidinyl)-1-piperazinyl]-4-isoquinolinyl]methanone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| N-[3-cyano-4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]cyclohexanecarboxamide | [no description available] | low | 0 | 0 | piperazines | |
| N-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-2-[(1-ethyl-2-oxo-4-quinolinyl)oxy]acetamide | [no description available] | low | 0 | 0 | piperazines | |
| N-(2-furanylmethyl)-N'-[4-methyl-2-(4-methyl-1-piperazinyl)-6-quinolinyl]butanediamide | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 7-[4-[4-(2-fluorophenyl)-1-piperazinyl]-4-oxobutyl]-6-sulfanylidene-5H-[1,3]dioxolo[4,5-g]quinazolin-8-one | [no description available] | low | 0 | 0 | piperazines | |
| 8-[[4-(5-chloro-2-methylphenyl)-1-piperazinyl]methyl]-3-methyl-7-(2-phenylethyl)purine-2,6-dione | [no description available] | low | 0 | 0 | piperazines | |
| N-(2-fluorophenyl)-3-[4-(2-fluorophenyl)-1-piperazinyl]propanamide | [no description available] | low | 0 | 0 | piperazines | |
| sb 258585 | [no description available] | low | 0 | 0 | piperazines | |
| [3-(4-methylphenyl)-1-phenyl-4-pyrazolyl]-[4-(2-pyridinyl)-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| (4-methylphenyl)-[4-[4-nitro-3-(3-pyridinylmethylamino)phenyl]-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines | |
| N-[3-[4-(4-fluorophenyl)-1-piperazinyl]-1,4-dioxo-2-naphthalenyl]benzenesulfonamide | [no description available] | low | 0 | 0 | piperazines | |
| [3-(2,3-dihydroindol-1-ylsulfonyl)phenyl]-[4-(2-pyridinyl)-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 3-(4-benzoyl-1-piperazinyl)-1-(2-methylpropyl)-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| rs 100329 | [no description available] | low | 0 | 0 | piperazines | |
| 2-methyl-5-[(4-phenyl-1-piperazinyl)-(3,4,5-trimethoxyphenyl)methyl]-6-thiazolo[3,2-b][1,2,4]triazolol | [no description available] | low | 0 | 0 | piperazines | |
| N-[[4-[[4-(4-fluorophenyl)-1-piperazinyl]-oxomethyl]cyclohexyl]methyl]-2-thiophenesulfonamide | [no description available] | low | 0 | 0 | piperazines | |
| pd 168,077 | [no description available] | low | 0 | 0 | piperazines | |
| N-[3-[4-(3-chlorophenyl)-1-piperazinyl]-1,4-dioxo-2-naphthalenyl]-2-thiophenesulfonamide | [no description available] | low | 0 | 0 | piperazines | |
| N-[3-(4-methyl-1-piperazinyl)-1,4-dioxo-2-naphthalenyl]benzenesulfonamide | [no description available] | low | 0 | 0 | 1,4-naphthoquinones; piperazines; sulfonamide | |
| 5-cyano-6-[4-(4-methoxyphenyl)-1-piperazinyl]-2-oxo-1H-pyridine-3-carboxylic acid ethyl ester | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 2-[4-(3-chlorophenyl)-1-piperazinyl]-3-pyridinecarboxylic acid propan-2-yl ester | [no description available] | low | 0 | 0 | isopropyl ester; piperazines; pyridines | |
| N-[3-fluoro-4-(4-phenyl-1-piperazinyl)phenyl]-2-(4-morpholinyl)acetamide | [no description available] | low | 0 | 0 | piperazines | |
| 3-(3,5-dimethyl-1-pyrazolyl)-6-[4-(4-fluorophenyl)-1-piperazinyl]-1,2,4,5-tetrazine | [no description available] | low | 0 | 0 | piperazines | |
| 2-(4-phenyl-1-piperazinyl)quinoxaline | [no description available] | low | 0 | 0 | piperazines | |
| 1-[4-(3-chlorophenyl)-1-piperazinyl]-2-phenyl-1-butanone | [no description available] | low | 0 | 0 | piperazines | |
| 6-amino-5-[2-[4-(2-methoxyphenyl)-1-piperazinyl]-1-oxoethyl]-1,3-dimethylpyrimidine-2,4-dione | [no description available] | low | 0 | 0 | piperazines | |
| mm 77 | [no description available] | low | 0 | 0 | piperazines | |
| 3-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-1,5-dihydropyrimido[5,4-b]indole-2,4-dione | [no description available] | low | 0 | 0 | piperazines; pyrimido-indole | |
| 4-(1H-benzimidazol-2-ylthio)-1-[4-(4-nitrophenyl)-1-piperazinyl]-1-butanone | [no description available] | low | 0 | 0 | piperazines | |
| [4-[(2-chlorophenyl)methylsulfonyl]-3-nitrophenyl]-[4-(2-pyridinyl)-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]-2-(3-pyridinyl)ethyl]-2-thiophenesulfonamide | [no description available] | low | 0 | 0 | piperazines | |
| 2-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-6,7,8,8a-tetrahydro-5H-imidazo[1,5-a]pyridine-1,3-dione | [no description available] | low | 0 | 0 | piperazines | |
| [4-(2,3-dimethylphenyl)-1-piperazinyl]-[5-[(4-methoxyphenyl)sulfonylmethyl]-2-furanyl]methanone | [no description available] | low | 0 | 0 | piperazines | |
| (6-bromo-5-methoxy-2-methyl-3-benzofuranyl)-[4-(2-methylphenyl)-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines | |
| 3-[3-[4-(4-methoxyphenyl)-1-piperazinyl]propyl]-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-4-one | [no description available] | low | 0 | 0 | piperazines | |
| N-[4-chloro-3-(trifluoromethyl)phenyl]-2-[4-(2-methoxyphenyl)-1-piperazinyl]acetamide | [no description available] | low | 0 | 0 | piperazines | |
| N-[[4-(2-ethoxyphenyl)-1-piperazinyl]-sulfanylidenemethyl]-1-adamantanecarboxamide | [no description available] | low | 0 | 0 | piperazines | |
| 3-(4-ethylphenyl)-4-hydroxy-4-[oxo-[4-(2-pyridinyl)-1-piperazinyl]methyl]-1H-quinazolin-2-one | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 5-[(4-phenyl-1-piperazinyl)-thiophen-2-ylmethyl]-6-thiazolo[3,2-b][1,2,4]triazolol | [no description available] | low | 0 | 0 | piperazines | |
| 2-[4-(5-chloro-2-methylphenyl)-1-piperazinyl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide | [no description available] | low | 0 | 0 | piperazines | |
| 1-[4-(2-fluorophenyl)-1-piperazinyl]-4-(4,4,6-trimethyl-2-sulfanylidene-1,3-diazinan-1-yl)-1-butanone | [no description available] | low | 0 | 0 | piperazines | |
| 1-(2-chloro-4-nitrophenyl)-4-(2-methoxyphenyl)piperazine | [no description available] | low | 0 | 0 | piperazines | |
| N-[6-amino-2,4-dioxo-1-(phenylmethyl)-5-pyrimidinyl]-N-ethyl-2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]acetamide | [no description available] | low | 0 | 0 | piperazines | |
| N,N-dimethyl-3-[[4-(4-nitrophenyl)-1-piperazinyl]-oxomethyl]-4-(1-pyrrolidinyl)benzenesulfonamide | [no description available] | low | 0 | 0 | piperazines | |
| 4-methyl-7-[[4-[[4-(4-nitrophenyl)-1-piperazinyl]-oxomethyl]phenyl]methoxy]-1-benzopyran-2-one | [no description available] | low | 0 | 0 | piperazines | |
| abt724 | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 1-[4-(2,3-dimethylphenyl)-1-piperazinyl]-3-(4,4,6-trimethyl-2-sulfanylidene-1,3-diazinan-1-yl)-1-propanone | [no description available] | low | 0 | 0 | piperazines | |
| 2-[(1-methyl-3-indolyl)thio]-1-(4-phenyl-1-piperazinyl)ethanone | [no description available] | low | 0 | 0 | piperazines | |
| 2-[4-(4-chloro-2-nitrophenyl)-1-piperazinyl]phenol | [no description available] | low | 0 | 0 | piperazines | |
| 2-(4-acetyl-1-piperazinyl)-6-amino-4-(cyanomethyl)pyridine-3,5-dicarbonitrile | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| [2-(1-piperidinyl)-1,3-benzothiazol-6-yl]-[4-(2-pyridinyl)-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| [4-(3-methoxyphenyl)-1-piperazinyl]-[2-(1-piperidinyl)-1,3-benzothiazol-6-yl]methanone | [no description available] | low | 0 | 0 | piperazines | |
| N-[3-[4-(2,5-dimethylphenyl)-1-piperazinyl]propyl]-2-(6-methyl-3-oxo-4H-1,4-benzoxazin-2-yl)acetamide | [no description available] | low | 0 | 0 | piperazines | |
| N-[2-(4-ethyl-1-piperazinyl)-4-methyl-6-quinolinyl]-2-pyrazinecarboxamide | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 6-[2-oxo-2-(4-phenyl-1-piperazinyl)ethyl]-3-(phenylmethyl)-7-triazolo[4,5-d]pyrimidinone | [no description available] | low | 0 | 0 | piperazines | |
| N-[1-[4-(2-methoxyphenyl)-1-piperazinyl]-1-thiophen-2-ylpropan-2-yl]benzenesulfonamide | [no description available] | low | 0 | 0 | piperazines | |
| l 745870 | [no description available] | low | 0 | 0 | piperazines | |
| kn 62 | [no description available] | low | 0 | 0 | piperazines | |
| (5R)-3'-phenyl-1-(phenylmethyl)spiro[1,3-diazinane-5,5'-2,4,4a,6-tetrahydro-1H-pyrazino[1,2-a]quinoline]-2,4,6-trione | [no description available] | low | 0 | 0 | piperazines | |
| 1-[4-[4-[[(2R)-2-(2,4-dichlorophenyl)-2-(1-imidazolylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]ethanone | [no description available] | low | 0 | 0 | piperazines | |
| [4-(3-chlorophenyl)sulfonyl-3-nitrophenyl]-[4-(2-pyridinyl)-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| N-[2-(4-acetyl-1-piperazinyl)phenyl]-2-(2-methylphenoxy)acetamide | [no description available] | low | 0 | 0 | piperazines | |
| (4-chloro-2-methyl-3-pyrazolyl)-[4-(2-ethoxyphenyl)-1-piperazinyl]methanone | [no description available] | low | 0 | 0 | piperazines | |
| l 750667 | [no description available] | low | 0 | 0 | piperazines | |
| 2-[4-(2-pyrimidinyl)-1-piperazinyl]quinoline | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 3-(1H-benzimidazol-2-yl)-1-[4-(2,4-dimethylphenyl)-1-piperazinyl]-1-propanone | [no description available] | low | 0 | 0 | piperazines | |
| LSM-17022 | [no description available] | low | 0 | 0 | piperazines | |
| 1-[4-(2,3-dimethylphenyl)-1-piperazinyl]-2-(1-methyl-3-indolyl)ethanone | [no description available] | low | 0 | 0 | piperazines | |
| pnu 96415e | [no description available] | low | 0 | 0 | piperazines | |
| n-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2h)-carboxamide | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| [4-(3-chlorophenyl)-1-piperazinyl]-(5-methyl-2-phenyl-3-pyrazolyl)methanone | [no description available] | low | 0 | 0 | piperazines | |
| PB28 | [no description available] | low | 0 | 0 | aromatic ether; piperazines; tetralins | anticoronaviral agent; antineoplastic agent; apoptosis inducer; sigma-2 receptor agonist |
| danusertib | [no description available] | low | 0 | 0 | piperazines | |
| hydroxynefazodone | [no description available] | low | 0 | 0 | piperazines | |
| N-(2,4-dimethoxyphenyl)-N-[2-[4-(4-methyl-1-piperazinyl)anilino]-4-pyrimidinyl]carbamic acid (2,6-dimethylphenyl) ester | [no description available] | low | 0 | 0 | piperazines | |
| 2-[2-fluoro-5-(4-methyl-1-piperazinyl)-4-nitrophenyl]-3,4-dihydro-1H-isoquinoline | [no description available] | low | 0 | 0 | piperazines | |
| 1-[4-[3-methyl-4-(3-methylphenyl)-1-piperazinyl]-3-nitrophenyl]piperidine-2,6-dione | [no description available] | low | 0 | 0 | piperazines | |
| [3-methyl-4-(3-methylphenyl)-1-piperazinyl]-[1-(7,8,9,10-tetrahydro-6H-purino[9,8-a]azepin-4-yl)-4-piperidinyl]methanone | [no description available] | low | 0 | 0 | piperazines | |
| [4-(2,3-dimethylphenyl)-1-piperazinyl]-[5-[(4-methylphenyl)sulfonylmethyl]-2-furanyl]methanone | [no description available] | low | 0 | 0 | piperazines | |
| [4-(3-chlorophenyl)-1-piperazinyl]-[1-[4-(2-pyridinyl)-1-piperazinyl]-4-isoquinolinyl]methanone | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| 1-butyl-3-[2-(4-ethyl-1-piperazinyl)-4-methyl-6-quinolinyl]-1-methylthiourea | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| N-[2-[4-(4-methoxyphenyl)-1-piperazinyl]ethyl]-6-sulfanylidene-5H-benzimidazolo[1,2-c]quinazoline-3-carboxamide | [no description available] | low | 0 | 0 | piperazines | |
| 1-[5-(diethylsulfamoyl)-2-(4-methyl-1-piperazinyl)phenyl]-3-(2-fluorophenyl)urea | [no description available] | low | 0 | 0 | piperazines | |
| 8-[1-(1,3-benzodioxol-5-yl)-3-(4-phenyl-1-piperazinyl)propyl]-5,7-dimethoxy-4-methyl-1-benzopyran-2-one | [no description available] | low | 0 | 0 | piperazines | |
| gdc 0941 | [no description available] | low | 0 | 0 | indazoles; morpholines; piperazines; sulfonamide; thienopyrimidine | EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor |
| 4-[4-(4-fluorophenyl)-1-piperazinyl]-N-[4-methyl-2-(4-morpholinyl)-6-quinolinyl]-4-oxobutanamide | [no description available] | low | 0 | 0 | piperazines | |
| cyclopropyl-[5-[[4-[[4-(2-methoxyphenyl)-1-piperazinyl]-oxomethyl]-1-piperidinyl]sulfonyl]-2-methyl-2,3-dihydroindol-1-yl]methanone | [no description available] | low | 0 | 0 | piperazines | |
| [5-[(2-methoxyphenoxy)methyl]-3-isoxazolyl]-(4-methyl-3-phenyl-1-piperazinyl)methanone | [no description available] | low | 0 | 0 | piperazines | |
| mk-1775 | [no description available] | low | 0 | 0 | piperazines | |
| navitoclax | [no description available] | low | 0 | 0 | aryl sulfide; monochlorobenzenes; morpholines; N-sulfonylcarboxamide; organofluorine compound; piperazines; secondary amino compound; sulfone; tertiary amino compound | antineoplastic agent; apoptosis inducer; B-cell lymphoma 2 inhibitor |
| 1-[4-[4-(2-furanylmethylamino)phenyl]-1-piperazinyl]ethanone | [no description available] | low | 0 | 0 | piperazines | |
| 1-[4-[4-[(5-bromo-2-furanyl)methylamino]phenyl]-1-piperazinyl]ethanone | [no description available] | low | 0 | 0 | piperazines | |
| N-[3-[[5-chloro-2-[4-(4-methyl-1-piperazinyl)anilino]-4-pyrimidinyl]oxy]phenyl]-2-propenamide | [no description available] | low | 0 | 0 | piperazines | |
| thiopental sodium | [no description available] | low | 0 | 0 | organochlorine compound; piperazines; pyrimidines | antineoplastic agent; tyrosine kinase inhibitor |
| LSM-2536 | [no description available] | low | 0 | 0 | piperazines | |
| N-(4,6-dimethyl-2-pyridinyl)-4-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinecarbothioamide | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| gsk-2816126 | [no description available] | low | 0 | 0 | piperazines; pyridines | |
| norclozapine | [no description available] | low | 0 | 0 | dibenzodiazepine; organochlorine compound; piperazines | delta-opioid receptor agonist; metabolite; serotonergic antagonist |
| 3-cyanopyridine | [no description available] | low | 0 | 0 | nitrile; pyridines | |
| 2-(3-pyridine)acetic acid | [no description available] | low | 0 | 0 | monocarboxylic acid; pyridines | human xenobiotic metabolite |
| nicotine 1-n-oxide | [no description available] | low | 0 | 0 | pyridines; pyrrolidine N-oxides | |
| norcotinine | [no description available] | low | 0 | 0 | pyridines; pyrrolidines | |
| 4-oxo-4-(3-pyridyl)butanoic acid | [no description available] | low | 0 | 0 | aromatic ketone; monocarboxylic acid; pyridines | |
| pyridine | [no description available] | low | 0 | 0 | azaarene; mancude organic heteromonocyclic parent; monocyclic heteroarene; pyridines | environmental contaminant; NMR chemical shift reference compound |
| carbinoxamine | [no description available] | low | 0 | 0 | monochlorobenzenes; pyridines; tertiary amino compound | anti-allergic agent; antiparkinson drug; H1-receptor antagonist; muscarinic antagonist |
| chlorpheniramine | [no description available] | low | 0 | 0 | monochlorobenzenes; pyridines; tertiary amino compound | anti-allergic agent; antidepressant; antipruritic drug; H1-receptor antagonist; histamine antagonist; serotonin uptake inhibitor |
| disopyramide | [no description available] | low | 0 | 0 | monocarboxylic acid amide; pyridines; tertiary amino compound | anti-arrhythmia drug |
| doxylamine | [no description available] | low | 0 | 0 | pyridines; tertiary amine | anti-allergic agent; antiemetic; antitussive; cholinergic antagonist; H1-receptor antagonist; histamine antagonist; sedative |
| fusaric acid | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| iproniazid | [no description available] | low | 0 | 0 | carbohydrazide; pyridines | |
| lansoprazole | [no description available] | low | 0 | 0 | benzimidazoles; pyridines; sulfoxide | anti-ulcer drug; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor |
| entinostat | [no description available] | low | 0 | 0 | benzamides; carbamate ester; primary amino compound; pyridines; substituted aniline | antineoplastic agent; apoptosis inducer; EC 3.5.1.98 (histone deacetylase) inhibitor |
| niflumic acid | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| omeprazole | [no description available] | low | 0 | 0 | aromatic ether; benzimidazoles; pyridines; sulfoxide | |
| pantoprazole | [no description available] | low | 0 | 0 | aromatic ether; benzimidazoles; organofluorine compound; pyridines; sulfoxide | anti-ulcer drug; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor; environmental contaminant; xenobiotic |
| pheniramine | [no description available] | low | 0 | 0 | pyridines; tertiary amino compound | |
| pinacidil | [no description available] | low | 0 | 0 | pyridines | |
| pioglitazone | [no description available] | low | 0 | 0 | aromatic ether; pyridines; thiazolidinediones | antidepressant; cardioprotective agent; EC 2.7.1.33 (pantothenate kinase) inhibitor; EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor; ferroptosis inhibitor; geroprotector; hypoglycemic agent; insulin-sensitizing drug; PPARgamma agonist; xenobiotic |
| pirbuterol | [no description available] | low | 0 | 0 | pyridines | |
| pyridinolcarbamate | [no description available] | low | 0 | 0 | pyridines | |
| rabeprazole | [no description available] | low | 0 | 0 | benzimidazoles; pyridines; sulfoxide | anti-ulcer drug; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor |
| sb 202190 | [no description available] | low | 0 | 0 | imidazoles; organofluorine compound; phenols; pyridines | apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| risedronic acid | [no description available] | low | 0 | 0 | pyridines | |
| imatinib | [no description available] | low | 0 | 0 | aromatic amine; benzamides; N-methylpiperazine; pyridines; pyrimidines | antineoplastic agent; apoptosis inducer; tyrosine kinase inhibitor |
| streptonigrin | [no description available] | low | 0 | 0 | pyridines; quinolone | antimicrobial agent; antineoplastic agent |
| sulfapyridine | [no description available] | low | 0 | 0 | pyridines; substituted aniline; sulfonamide antibiotic; sulfonamide | antiinfective agent; dermatologic drug; drug allergen; environmental contaminant; xenobiotic |
| tazarotene | [no description available] | low | 0 | 0 | acetylenic compound; ethyl ester; pyridines; retinoid; thiochromane | keratolytic drug; prodrug; teratogenic agent |
| n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine | [no description available] | low | 0 | 0 | N-substituted diamine; pyridines; tertiary amino compound | apoptosis inducer; chelator; copper chelator |
| thurfyl nicotinate | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| brompheniramine | [no description available] | low | 0 | 0 | organobromine compound; pyridines | anti-allergic agent; H1-receptor antagonist |
| methyl nicotinate | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| citrazinic acid | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| nicotinyl alcohol | [no description available] | low | 0 | 0 | aromatic primary alcohol; pyridines | antilipemic drug; vasodilator agent |
| beta-nicotyrine | [no description available] | low | 0 | 0 | pyridines | |
| 3-ethylpyridine | [no description available] | low | 0 | 0 | pyridines | |
| 2-Pyridinylmethanol | [no description available] | low | 0 | 0 | pyridines | |
| nicoboxil | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| clopyralid | [no description available] | low | 0 | 0 | organochlorine pesticide; pyridines | herbicide |
| oxiniacic acid | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 2-(aminomethyl)pyridine | [no description available] | low | 0 | 0 | pyridines | |
| propiram | [no description available] | low | 0 | 0 | pyridines | |
| n'-nitrosonornicotine | [no description available] | low | 0 | 0 | pyridines; pyrrolidines | |
| 5-hydroxynicotinic acid | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine | [no description available] | low | 0 | 0 | pyridines | |
| 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone | [no description available] | low | 0 | 0 | nitrosamine; pyridines | |
| haloxyfop | [no description available] | low | 0 | 0 | aromatic ether; monocarboxylic acid; organochlorine compound; organofluorine compound; pyridines | |
| fluazifop-butyl | [no description available] | low | 0 | 0 | aromatic ether; carboxylic ester; organofluorine compound; pyridines | |
| imazapyr, (+-)-isomer | [no description available] | low | 0 | 0 | imidazolines; imidazolone; pyridinemonocarboxylic acid; pyridines | |
| imazethapyr | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 2,2'-dipyridyl disulfide | [no description available] | low | 0 | 0 | organic disulfide; pyridines | oxidising agent |
| droxicam | [no description available] | low | 0 | 0 | organic heterotricyclic compound; pyridines | cyclooxygenase 1 inhibitor; hepatotoxic agent; non-narcotic analgesic; non-steroidal anti-inflammatory drug; platelet aggregation inhibitor; prodrug |
| methyridine | [no description available] | low | 0 | 0 | pyridines | |
| picosulfate sodium | [no description available] | low | 0 | 0 | aryl sulfate; pyridines | |
| 2-hydroxynicotinic acid | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| ethylnicotinate | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| nicametate | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| nicotinamide n-oxide | [no description available] | low | 0 | 0 | pyridines | |
| nicosulfuron | [no description available] | low | 0 | 0 | N-sulfonylurea; pyridines; pyrimidines | environmental contaminant; herbicide; xenobiotic |
| 4,4'-dipyridyl disulfide | [no description available] | low | 0 | 0 | organic disulfide; pyridines | |
| 2-Chloronicotinic acid | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 4-methoxymethylpyridoxine | [no description available] | low | 0 | 0 | pyridines | |
| 6-chloronicotinic acid | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 2-pyridylacetic acid | [no description available] | low | 0 | 0 | pyridines | |
| fluazifop | [no description available] | low | 0 | 0 | aromatic ether; monocarboxylic acid; organofluorine compound; pyridines | |
| pyriproxyfen | [no description available] | low | 0 | 0 | aromatic ether; pyridines | juvenile hormone mimic |
| dithiopyr | [no description available] | low | 0 | 0 | organofluorine compound; pyridines; thioester | |
| thiazopyr | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| dpx e9636 | [no description available] | low | 0 | 0 | aromatic ether; N-sulfonylurea; pyridines; pyrimidines; sulfone | environmental contaminant; herbicide; xenobiotic |
| clodinafop-propargyl | [no description available] | low | 0 | 0 | aromatic ether; carboxylic ester; organochlorine compound; organofluorine compound; propyzamide; pyridines | agrochemical; EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor; herbicide |
| flazasulfuron | [no description available] | low | 0 | 0 | pyridines; sulfonamide | |
| 2,6-dichloroisonicotinic acid | [no description available] | low | 0 | 0 | monocarboxylic acid; organochlorine compound; pyridines | EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor |
| difenpiramide | [no description available] | low | 0 | 0 | biphenyls; monocarboxylic acid amide; pyridines | antipyretic; non-narcotic analgesic; non-steroidal anti-inflammatory drug |
| 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol | [no description available] | low | 0 | 0 | nitrosamine; pyridines; secondary alcohol | biomarker; carcinogenic agent; human urinary metabolite |
| hydroxycotinine | [no description available] | low | 0 | 0 | N-alkylpyrrolidine; pyridines; pyrrolidin-2-ones; pyrrolidine alkaloid | |
| 5-hydroxymethylomeprazole | [no description available] | low | 0 | 0 | aromatic ether; benzimidazoles; pyridines; sulfoxide | drug metabolite |
| forasartan | [no description available] | low | 0 | 0 | benzenes; pyridines; tetrazoles; triazoles | angiotensin receptor antagonist; antihypertensive agent |
| abiraterone | [no description available] | low | 0 | 0 | 3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; pyridines | antineoplastic agent; EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor |
| agn 190299 | [no description available] | low | 0 | 0 | monocarboxylic acid; pyridines; retinoid; thiochromane | keratolytic drug; teratogenic agent |
| vatalanib | [no description available] | low | 0 | 0 | monochlorobenzenes; phthalazines; pyridines; secondary amino compound | angiogenesis inhibitor; antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; vascular endothelial growth factor receptor antagonist |
| metyrapol | [no description available] | low | 0 | 0 | pyridines | |
| sb 203580 | [no description available] | low | 0 | 0 | imidazoles; monofluorobenzenes; pyridines; sulfoxide | EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; geroprotector; Hsp90 inhibitor; neuroprotective agent |
| aminopyralid | [no description available] | low | 0 | 0 | aromatic amine; organochlorine pesticide; pyridines | herbicide |
| dabigatran etexilate | [no description available] | low | 0 | 0 | aromatic amide; benzimidazoles; beta-alanine derivative; carboxamidine; carboxylic ester; pyridines | anticoagulant; EC 3.4.21.5 (thrombin) inhibitor; prodrug |
| dabigatran | [no description available] | low | 0 | 0 | aromatic amide; benzimidazoles; beta-alanine derivative; carboxamidine; pyridines | anticoagulant; EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor; EC 3.4.21.5 (thrombin) inhibitor |
| 6-methyl-2-oxo-4-(trifluoromethyl)-1H-pyridine-3-carbonitrile | [no description available] | low | 0 | 0 | nitrile; pyridines | |
| gant58 | [no description available] | low | 0 | 0 | pyridines | |
| 3-(3-pyridinyl)propanoic acid | [no description available] | low | 0 | 0 | pyridines | |
| rosoxacin | [no description available] | low | 0 | 0 | pyridines; quinolinemonocarboxylic acid; quinolone antibiotic | antibacterial drug; antiinfective agent |
| gant 61 | [no description available] | low | 0 | 0 | aminal; dialkylarylamine; pyridines; substituted aniline; tertiary amino compound | antineoplastic agent; apoptosis inducer; glioma-associated oncogene inhibitor; Hedgehog signaling pathway inhibitor |
| e 3040 | [no description available] | low | 0 | 0 | benzothiazoles; organic hydroxy compound; pyridines; secondary amino compound | anti-inflammatory drug; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; uricosuric drug |
| E3040 glucuronide | [no description available] | low | 0 | 0 | benzothiazoles; beta-D-glucosiduronic acid; pyridines; secondary amino compound | xenobiotic metabolite |
| cerivastatin | [no description available] | low | 0 | 0 | dihydroxy monocarboxylic acid; pyridines; statin (synthetic) | |
| hts 466284 | [no description available] | low | 0 | 0 | pyrazoles; pyridines; quinolines | TGFbeta receptor antagonist |
| prinomastat | [no description available] | low | 0 | 0 | aromatic ether; hydroxamic acid; pyridines; sulfonamide; thiomorpholines | antineoplastic agent; EC 3.4.24.35 (gelatinase B) inhibitor; matrix metalloproteinase inhibitor |
| 6-methyl-2-oxo-5-[oxo-(1-phenylethylamino)methyl]-1H-pyridine-3-carboxylic acid ethyl ester | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 5-(2-furanyl)-3-(3-pyridinyl)-1,2,4-oxadiazole | [no description available] | low | 0 | 0 | pyridines | |
| 1-(2-pyridin-4-yl-1-oxa-3,4-diazaspiro[4.6]undec-2-en-4-yl)ethanone | [no description available] | low | 0 | 0 | pyridines | |
| s 1033 | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes; imidazoles; pyridines; pyrimidines; secondary amino compound; secondary carboxamide | anticoronaviral agent; antineoplastic agent; tyrosine kinase inhibitor |
| 2-pyridinecarboxylic acid [2-(2,3-dichloroanilino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| N-methyl-N-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)-3-oxolanecarboxamide | [no description available] | low | 0 | 0 | pyridines | |
| 5-(4-propylcyclohexyl)-3-(3-pyridinyl)-1,2,4-oxadiazole | [no description available] | low | 0 | 0 | pyridines | |
| N-methyl-N-[5-(2-pyridinyl)-1,3,4-thiadiazol-2-yl]-3-oxolanecarboxamide | [no description available] | low | 0 | 0 | pyridines | |
| 2-methoxy-N-methyl-N-[5-(2-pyridinyl)-1,3,4-thiadiazol-2-yl]acetamide | [no description available] | low | 0 | 0 | pyridines | |
| 6-hydroxy-1-(3-hydroxypropyl)-4-methyl-2-oxo-5-(1-piperidinylmethyl)-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | nitrile; pyridines | |
| 5-ethyl-4,6-dimethyl-2-sulfanylidene-1H-pyridine-3-carbonitrile | [no description available] | low | 0 | 0 | nitrile; pyridines | |
| N-(4-{[2-(pyridin-3-yl)piperidin-1-yl]sulfonyl}phenyl)acetamide | [no description available] | low | 0 | 0 | acetamides; piperidines; pyridines; sulfonamide | |
| prothionamide | [no description available] | low | 0 | 0 | pyridines | |
| 1-(4-methyl-1,2,5-oxadiazol-3-yl)-3-(3-pyridinyl)urea | [no description available] | low | 0 | 0 | pyridines | |
| N-(3-fluorophenyl)-2-(pyridin-4-yl)quinazolin-4-amine | [no description available] | low | 0 | 0 | aromatic amine; monofluorobenzenes; pyridines; quinazolines; secondary amino compound; substituted aniline | |
| 5-cyano-2-methyl-6-sulfanylidene-1H-pyridine-3-carboxylic acid ethyl ester | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 2-(1H-imidazol-1-yl)-5-(trifluoromethyl)pyridine | [no description available] | low | 0 | 0 | pyridines | |
| 5-(3-pyridinylmethyl)-1,3,5-triazinane-2-thione | [no description available] | low | 0 | 0 | pyridines | |
| cotinine | [no description available] | low | 0 | 0 | N-alkylpyrrolidine; pyridines; pyrrolidin-2-ones; pyrrolidine alkaloid | antidepressant; biomarker; human xenobiotic metabolite; plant metabolite |
| 2-(2,6-dichloroanilino)-3-pyridinesulfonamide | [no description available] | low | 0 | 0 | pyridines; sulfonamide | |
| 4-(4-chloroanilino)-3-pyridinesulfonamide | [no description available] | low | 0 | 0 | pyridines; sulfonamide | |
| 6-(2-oxopropylthio)-3-pyridinecarboxylic acid | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 6-chloro-N-(2-hydroxyphenyl)-3-pyridinesulfonamide | [no description available] | low | 0 | 0 | pyridines; sulfonamide | |
| 3-(phenylmethyl)-6-pyridin-4-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole | [no description available] | low | 0 | 0 | pyridines; triazolothiadiazole | |
| 5-bromo-6-chloro-N-(4-methyl-2-pyridinyl)-3-pyridinesulfonamide | [no description available] | low | 0 | 0 | pyridines; sulfonamide | |
| pyrabactin | [no description available] | low | 0 | 0 | naphthalenes; organobromine compound; pyridines; sulfonamide | abscisic acid receptor agonist; hormone; plant growth regulator |
| 1-ethyl-3-sulfanylidene-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile | [no description available] | low | 0 | 0 | pyridines | |
| 6-tert-butyl-2-oxo-4-(trifluoromethyl)-1H-pyridine-3-carbonitrile | [no description available] | low | 0 | 0 | nitrile; pyridines | |
| N,N-dibutyl-2-(pyridin-4-yl)quinazolin-4-amine | [no description available] | low | 0 | 0 | pyridines; quinazolines; tertiary amino compound | |
| 4,6-dimethyl-2-[3-(4-morpholinyl)propylamino]-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | nitrile; pyridines | |
| 2-ethoxy-3-pyridinecarboxylic acid [2-[1-(2-furanylmethyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| mcb-613 | [no description available] | low | 0 | 0 | cyclic ketone; enone; pyridines | antineoplastic agent; steroid receptor coactivator stimulator |
| 5,6-dichloro-3-pyridinecarboxylic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 4-pyridinecarboxylic acid [2-[1-(2-furanylmethyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 2-oxo-1H-pyridine-3-carboxylic acid [2-(2,5-dimethyl-1-propyl-3-pyrrolyl)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 2-thiopyridine | [no description available] | low | 0 | 0 | aryl thiol; pyridines | allergen; fluorescence quencher |
| 2-(methylamino)-6-thiophen-2-yl-4-(trifluoromethyl)-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | nitrile; pyridines | |
| 2-(1-piperidinyl)-6-thiophen-2-yl-4-(trifluoromethyl)-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | nitrile; pyridines | |
| N-benzyl-N'-methyl-N-(pyridin-3-ylmethyl)thiourea | [no description available] | low | 0 | 0 | pyridines | |
| 3-Chloro-5-(trifluoromethyl)pyridine-2-carbothioamide | [no description available] | low | 0 | 0 | pyridines | |
| 2,6-dimethyl-4-(3-thienyl)pyridine-3,5-dicarboxylic acid | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 5-cyano-2-(methoxymethyl)-6-sulfanylidene-1H-pyridine-3-carboxylic acid methyl ester | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| ethionamide | [no description available] | low | 0 | 0 | pyridines; thiocarboxamide | antilipemic drug; antitubercular agent; fatty acid synthesis inhibitor; leprostatic drug; prodrug |
| 2-(propylthio)nicotinic acid | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 5-Chloro-2-hydroxy-4,6-dimethylnicotinonitrile | [no description available] | low | 0 | 0 | nitrile; pyridines | |
| 3-[1-(2,4-dichlorophenyl)sulfonyl-2-pyrrolidinyl]pyridine | [no description available] | low | 0 | 0 | pyridines; pyrrolidines | |
| 2-oxo-4,6-dithiophen-2-yl-1H-pyridine-3-carbonitrile | [no description available] | low | 0 | 0 | nitrile; pyridines | |
| 6-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-N-ethyl-N-phenyl-3-pyridinesulfonamide | [no description available] | low | 0 | 0 | pyridines; sulfonamide | |
| alpha-nicotyrine | [no description available] | low | 0 | 0 | pyridines | |
| dapiprazole | [no description available] | low | 0 | 0 | N-alkylpiperazine; N-arylpiperazine; pyridines | alpha-adrenergic antagonist; antipsychotic agent; miotic; ophthalmology drug |
| glucitol hexanicotinate | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 6,8-difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline | [no description available] | low | 0 | 0 | organic heterotricyclic compound; organofluorine compound; pyridines; secondary amino compound | |
| N-(1,3-benzodioxol-5-ylmethyl)-N-[2-(cyclohexylamino)-2-oxo-1-pyridin-4-ylethyl]-2,2,2-trifluoroacetamide | [no description available] | low | 0 | 0 | benzodioxoles; pyridines; secondary carboxamide; tertiary carboxamide; trifluoroacetamide | |
| 1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[(2-pyridinylthio)methyl]-4-triazolecarboxylic acid propan-2-yl ester | [no description available] | low | 0 | 0 | aryl sulfide; azole; isopropyl ester; oxadiazole; pyridines | |
| 2-pyridinecarboxylic acid [2-(5-chloro-2-thiophenyl)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 2-[[2-[(2-methoxyphenyl)methylamino]-2-oxoethyl]thio]-3-pyridinecarboxylic acid [2-[(2-methoxyphenyl)methylamino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 2-[(5-formyl-2-methoxyphenyl)methylthio]-3-pyridinecarboxylic acid | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 3-(1-hydroxy-5,5-dimethyl-4-phenyl-2H-imidazol-2-yl)pyridine | [no description available] | low | 0 | 0 | pyridines | |
| 2-pyridinecarboxylic acid [2-[2-(difluoromethoxy)anilino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| hydroxypioglitazone | [no description available] | low | 0 | 0 | aromatic ether; pyridines; thiazolidinediones | human xenobiotic metabolite |
| 2-(2-fluoroanilino)-3-pyridinecarboxylic acid [2-[(1,1-dioxo-3-thiolanyl)-methylamino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide | [no description available] | low | 0 | 0 | benzamides; benzodioxoles; imidazoles; pyridines | EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| N-(1-benzylpiperidin-4-yl)-2-(pyridin-3-yl)quinazolin-4-amine | [no description available] | low | 0 | 0 | aromatic amine; piperidines; pyridines; quinazolines; secondary amino compound; tertiary amino compound | |
| triprolidine | [no description available] | low | 0 | 0 | N-alkylpyrrolidine; olefinic compound; pyridines | H1-receptor antagonist |
| pibutidine | [no description available] | low | 0 | 0 | aromatic ether; cyclobutenones; olefinic compound; piperidines; primary amino compound; pyridines; secondary amino compound | anti-ulcer drug; H2-receptor antagonist |
| acrivastine | [no description available] | low | 0 | 0 | alpha,beta-unsaturated monocarboxylic acid; N-alkylpyrrolidine; olefinic compound; pyridines | H1-receptor antagonist |
| 2-[3-(diethylamino)propylamino]-4-(methoxymethyl)-6-methyl-3-pyridinecarbonitrile | [no description available] | low | 0 | 0 | nitrile; pyridines | |
| clodinafop | [no description available] | low | 0 | 0 | aromatic ether; monocarboxylic acid; organochlorine compound; organofluorine compound; pyridines | EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor; phenoxy herbicide |
| 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one | [no description available] | low | 0 | 0 | enone; pyridines | angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; autophagy inducer; EC 2.7.1.105 (6-phosphofructo-2-kinase) inhibitor |
| axitinib | [no description available] | low | 0 | 0 | aryl sulfide; benzamides; indazoles; pyridines | antineoplastic agent; tyrosine kinase inhibitor; vascular endothelial growth factor receptor antagonist |
| (2-Chloro-4-pyridinyl)methanol | [no description available] | low | 0 | 0 | organohalogen compound; pyridines | |
| pymetrozine | [no description available] | low | 0 | 0 | 1,2,4-triazines; pyridines | antifeedant; environmental contaminant; TRPV channel modulator; xenobiotic |
| abiraterone acetate | [no description available] | low | 0 | 0 | pyridines; sterol ester | antineoplastic agent; EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor; prodrug |
| mocetinostat | [no description available] | low | 0 | 0 | aminopyrimidine; benzamides; pyridines; secondary amino compound; secondary carboxamide; substituted aniline | antineoplastic agent; apoptosis inducer; autophagy inducer; cardioprotective agent; EC 3.5.1.98 (histone deacetylase) inhibitor; hepatotoxic agent |
| 4-(1H-imidazol-5-ylmethyl)pyridine | [no description available] | low | 0 | 0 | pyridines | |
| 680c91 | [no description available] | low | 0 | 0 | fluoroindole; olefinic compound; pyridines | EC 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitor |
| masitinib | [no description available] | low | 0 | 0 | 1,3-thiazoles; benzamides; N-alkylpiperazine; pyridines | antineoplastic agent; antirheumatic drug; tyrosine kinase inhibitor |
| vorapaxar | [no description available] | low | 0 | 0 | carbamate ester; lactone; naphthofuran; organofluorine compound; pyridines | cardiovascular drug; platelet aggregation inhibitor; protease-activated receptor-1 antagonist |
| azd2858 | [no description available] | low | 0 | 0 | aromatic amine; N-methylpiperazine; pyrazines; pyridines; secondary carboxamide; sulfonamide | antineoplastic agent; bone density conservation agent; EC 2.7.11.26 (tau-protein kinase) inhibitor; Wnt signalling activator |
| ciclonicate | [no description available] | low | 0 | 0 | aromatic carboxylic acid; pyridines | |
| tedizolid | [no description available] | low | 0 | 0 | carbamate ester; organofluorine compound; oxazolidinone; primary alcohol; pyridines; tetrazoles | antimicrobial agent; drug metabolite; protein synthesis inhibitor |
| chlorantranilipole | [no description available] | low | 0 | 0 | monochlorobenzenes; organobromine compound; pyrazole insecticide; pyrazoles; pyridines; secondary carboxamide | ryanodine receptor agonist |
| picoxystrobin | [no description available] | low | 0 | 0 | aromatic ether; enoate ester; enol ether; methoxyacrylate strobilurin antifungal agent; organofluorine compound; pyridines | antifungal agrochemical; mitochondrial cytochrome-bc1 complex inhibitor |
| tedizolid phosphate | [no description available] | low | 0 | 0 | carbamate ester; organofluorine compound; oxazolidinone; phosphate monoester; pyridines; tetrazoles | antimicrobial agent; prodrug; protein synthesis inhibitor |
| dorsomorphin | [no description available] | low | 0 | 0 | aromatic ether; piperidines; pyrazolopyrimidine; pyridines | bone morphogenetic protein receptor antagonist; EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitor |
| cyantraniliprole | [no description available] | low | 0 | 0 | nitrile; organobromine compound; organochlorine compound; pyrazole insecticide; pyridines; secondary carboxamide | ryanodine receptor agonist |
| GDC-0879 | [no description available] | low | 0 | 0 | indanes; ketoxime; primary alcohol; pyrazoles; pyridines | antineoplastic agent; B-Raf inhibitor |
| bgt226 | [no description available] | low | 0 | 0 | aromatic ether; imidazoquinoline; N-arylpiperazine; organofluorine compound; pyridines | antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor |
| dafadine C | [no description available] | low | 0 | 0 | aromatic amide; aromatic ether; difluorobenzene; isoxazoles; N-acylpiperidine; pyridines | P450 inhibitor |
| dafadine B | [no description available] | low | 0 | 0 | aromatic amide; aromatic ether; isoxazoles; monochlorobenzenes; monofluorobenzenes; N-acylpiperidine; pyridines | P450 inhibitor |
| lumacaftor | [no description available] | low | 0 | 0 | aromatic amide; benzodioxoles; benzoic acids; cyclopropanes; organofluorine compound; pyridines | CFTR potentiator; orphan drug |
| ro5126766 | [no description available] | low | 0 | 0 | aryloxypyrimidine; coumarins; organofluorine compound; pyridines; sulfamides | antineoplastic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| sulfoxaflor | [no description available] | low | 0 | 0 | nitrile; organofluorine compound; pyridines; sulfoximide | |
| cnf 2024 | [no description available] | low | 0 | 0 | 2-aminopurines; aromatic ether; organochlorine compound; pyridines | antineoplastic agent; Hsp90 inhibitor |
| gdc 0449 | [no description available] | low | 0 | 0 | benzamides; monochlorobenzenes; pyridines; sulfone | antineoplastic agent; Hedgehog signaling pathway inhibitor; SMO receptor antagonist; teratogenic agent |
| bms 754807 | [no description available] | low | 0 | 0 | pyrazoles; pyridines; pyrrolidines; pyrrolotriazine | antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| 4-(1-((5-((2,6-dimethylphenoxy)methyl)-3-isoxazolyl)carbonyl)-4-piperidinyl)pyridine | [no description available] | low | 0 | 0 | aromatic amide; aromatic ether; isoxazoles; N-acylpiperidine; pyridines | geroprotector; P450 inhibitor |
| dafadine D | [no description available] | low | 0 | 0 | aromatic amide; aromatic ether; isoxazoles; N-acylpiperidine; organofluorine compound; pyridines | P450 inhibitor |
| dafadine O | [no description available] | low | 0 | 0 | aromatic amide; aromatic ether; isoxazoles; N-acylpiperidine; pyridines; ring assembly | P450 inhibitor |
| florbetapir f 18 | [no description available] | low | 0 | 0 | (18)F radiopharmaceutical; aromatic ether; organofluorine compound; pyridines; substituted aniline | radioactive imaging agent |
| sch772984 | [no description available] | low | 0 | 0 | biaryl; indazoles; N-acylpiperazine; N-alkylpyrrolidine; N-arylpiperazine; pyridines; pyrimidines; pyrrolidinecarboxamide; secondary carboxamide; tertiary amino compound; tertiary carboxamide | analgesic; antineoplastic agent; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| gsk 2126458 | [no description available] | low | 0 | 0 | aromatic ether; difluorobenzene; pyridazines; pyridines; quinolines; sulfonamide | anticoronaviral agent; antineoplastic agent; autophagy inducer; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor; radiosensitizing agent |
| 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-(2-pyridinylsulfonyl)piperazine | [no description available] | low | 0 | 0 | pyridines; sulfonamide | |
| ml228 probe | [no description available] | low | 0 | 0 | 1,2,4-triazines; biphenyls; pyridines; secondary amino compound | hypoxia-inducible factor pathway activator |
| lgk974 | [no description available] | low | 0 | 0 | bipyridines; pyrazines; pyridines; secondary carboxamide | Wnt signalling inhibitor |
| afidopyropen | [no description available] | low | 0 | 0 | cyclopropanecarboxylate ester; organic heterotetracyclic compound; pyridines; secondary alcohol | agrochemical; insecticide; TRPV channel modulator |
| piroxicam | [no description available] | low | 0 | 0 | benzothiazine; monocarboxylic acid amide; pyridines | analgesic; antirheumatic drug; cyclooxygenase 1 inhibitor; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-steroidal anti-inflammatory drug |
| mobiflex | [no description available] | low | 0 | 0 | heteroaryl hydroxy compound; monocarboxylic acid amide; pyridines; thienothiazine | antipyretic; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug |
| lornoxicam | [no description available] | low | 0 | 0 | heteroaryl hydroxy compound; monocarboxylic acid amide; organochlorine compound; pyridines; thienothiazine | antipyretic; non-narcotic analgesic; non-steroidal anti-inflammatory drug |
| MK-8353 | [no description available] | low | 0 | 0 | aromatic ether; dihydropyridine; indazoles; methyl sulfide; N-alkylpyrrolidine; pyridines; pyrrolidinecarboxamide; secondary carboxamide; tertiary carboxamide; triazoles | antineoplastic agent; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| acp-196 | [no description available] | low | 0 | 0 | aromatic amine; benzamides; imidazopyrazine; pyridines; pyrrolidinecarboxamide; secondary carboxamide; tertiary carboxamide; ynone | antineoplastic agent; apoptosis inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor |
| GSK1059615 | [no description available] | low | 0 | 0 | pyridines; quinolines; thiazolidinone | antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor |
| pf-06687252 | [no description available] | low | 0 | 0 | azabicycloalkane; enone; phenols; pyridines | |
| 2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1h-indole-5-carbonitrile | [no description available] | low | 0 | 0 | hydroxyindoles; morpholines; nitrile; pyridines; tertiary amino compound | antineoplastic agent; apoptosis inducer; EC 2.7.11.26 (tau-protein kinase) inhibitor; tau aggregation inhibitor |
| sb-590885 | [no description available] | low | 0 | 0 | aromatic ether; imidazoles; ketoxime; pyridines; tertiary amino compound |
| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|---|---|---|---|
| Inflammation | 0 | low | 1 | 0 |
| Innate Inflammatory Response | 0 | low | 1 | 0 |
| Malaria, Falciparum | 0 | low | 1 | 0 |
| Plasmodium falciparum Malaria | 0 | low | 1 | 0 |